Season One features 22 episodes that aired in the United States beginning September 13, 2005, and ending May 4, 2006. The first sixteen episodes aired on Tuesdays at 9:00 pm, after which the series was rescheduled to Thursdays.[103] Sam and Dean Winchester lost their mother as children in a fire with supernatural elements. As a result, their father devoted his life to finding out what killed his wife so that he could seek revenge. He brought his sons on the road with him, training them to fight evil. Sam left this life as a "hunter" in order to attend college at Stanford University, while Dean stayed with their father. However, when their father goes missing while on a hunting trip, Dean asks Sam for help in locating him. Sam's girlfriend Jess is soon killed in the same supernatural manner that ended their mother's life, and Sam drops out of school in order to hunt the thing that killed her. They save innocent people along the way from supernatural creatures, and Sam starts developing psychic abilities. They eventually find their father, who reveals that the creature they seek is a yellow-eyed demon and that he plans to end its life with a mystical Colt revolver that can kill anything.
Sam - Jared Padalecki
and Dean Winchester - Jensen Ackles
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