MORGELLONS HORROW SHOW 6: YARN IN SKIN

Correction: At 1:06, word should be spelled MICROARRAYS.
YARN: The yarn is made by transgenic bacteria. Yarn was found in the skin of a woman who has Morgellons.

Morgellons involves conserved-signaling components which can be used across kingdoms and adapted to produce synthetic eukaryotic signal transduction pathways.

Email: June.Medford@colostate.edu

"ENGINEERING KEY COMPONENTS IN A SYNTHETIC EUKARYOTIC SIGNAL TRANSDUCTION PATHWAY"
Molecular Systems Biology
Published May 19, 2009
Signal transduction underlies how living organisms detect and respond to stimuli. A goal of synthetic biology is to rewire natural signal transduction systems. Bacteria, yeast, and plants sense environmental aspects through conserved histidine kinase (HK) signal transduction systems. HK protein components are typically comprised of multiple, relatively modular, and conserved domains. Phosphate transfer between these components may exhibit considerable cross talk between the otherwise apparently linear pathways, thereby establishing networks that integrate multiple signals. We show that sequence conservation and cross talk can extend across kingdoms and can be exploited to produce a synthetic plant signal transduction system. In response to HK cross talk, heterologously expressed bacterial response regulators, PhoB and OmpR, translocate to the nucleus on HK activation. Using this discovery, combined with modification of PhoB (PhoB-VP64), we produced a key component of a eukaryotic synthetic signal transduction pathway. In response to exogenous cytokinin, PhoB-VP64 translocates to the nucleus, binds a synthetic PlantPho promoter, and activates gene expression. These results show that conserved-signaling components can be used across kingdoms and adapted to produce synthetic eukaryotic signal transduction pathways.

Living organisms sense and respond to their environments using an array of signal transduction systems. Better understanding of natural signaling, as well as 'rewiring' systems to produce new biological functions and potential biotechnological applications, are goals of synthetic biology. Bacteria, fungi, and plants use histidine kinase (HK) or two-component systems to sense environmental factors, such as the presence of ligands, osmotic and oxidative conditions, or pathogenic factors (Stock et al, 2000; Mizuno, 2005; Nemecek et al, 2006). HK-based signal transduction systems exhibit relatively modular architecture built from a limited number of protein domains, with individual domains often conserved across pathways and species (Koretke et al, 2000; Stock et al, 2000; Ferreira and Kieber, 2005; Mizuno, 2005; Zhang and Shi, 2005). Information transfer in signal transduction systems may not be linear; components can exhibit cross talk to establish networks that integrate multiple signals (Hass et al, 2004; Laub and Goulian, 2007). Modular components and the cross talk between them are postulated to be crucial in the evolution of complex signal transduction pathways (Aharoni et al, 2005; Bhattacharyya et al, 2006). For example, new connectivities are thought to have evolved through the (re)arrangement of components in various combinations and compositions (Aharoni et al, 2005; Bhattacharyya et al, 2006).

http://www.ncbi.nlm.nih.gov/sites/ppmc/articles/PMC2694678/

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[TheComingEvents2012]

These work on frequency waves that are being produced and the chemtrails are part of the program by spreading Morgellons and our food and water.

[TheComingEvents2012]

@mrgmakin Please Goto Strange days Strange skies.If you don't know whats going on.

[melschmi]

i still dont understand how this illness works... how can it be all at the same time?!?!

[VonHeintz]

what are the arthropods can't see em. am i missing something obvious

[mythtree]

DEAR NASA - MAY WE HAVE THE CURE PLEASE?

that is what should be written in the skies...

[PaulF247]

Thank you for all your good work. I would love to send you a photo of the Worm/Creatures that came out of my cotton baseball cap after boiling it first then spraying Clean Green enzyme on it and placing it in the Microwave for 2 minutes. Horrific entity that did not die from all that, just emerged from the weave of the cotton and expanded due to the Microwaves.

[z0nt21]

@mrgmakin Biological & Gene Warfare, delivery methods most often used are via aerial delivery systems, such as aerosols.

Very interesting, if they wanted to cull population and this is not a mere experiment, then a weapon targeting specific groups, or races with sterility properties would've been perfect.

[mrgmakin]

I have watched a few of your Morgellons videos and exucse my ignorance, but I still don't understand what it is. Such a diverse and seemingly unconnected array of strange objects, both organic and inorganic, emerging from peoples' skin? How do they get there? Why? I do not understand, but it is distressing and frightening for sure.

[DannysCam]

wow thats messed up i never heard of this befor

[kiohitita]

greetings