Stem Cells Breakethrough - Dramatic Change in Patient with ALS and MG following BrainStorm's Therapy

July 3, 2012
Israeli Channel 2 reports: Dramatic Change in Patient with ALS and MG following Compassionate Use of BrainStorm's Nurown™ Cell Therapy
‫NY, Petach Tikva, July 2, 2012. -- BrainStorm Cell Therapeutics Inc. (OTC BB: BCLI), Israeli Channel 2 TV interviewed today a patient suffering from Myasthenia Gravis (MG) and recently diagnosed with ALS. The patient reported that he has experienced visible improvement in his speech, walking, balance, posture, muscle strength, appetite, digestion, and weight gain following compassionate treatment with BrainStorm's NurOwn cell therapy.
"Due to the rare disease combination of MG and ALS, this patient was approved for compassionate treatment with BrainStorm's NurOwn cell therapy" says Professor Dimitrios Karussis of the Neurology Department at The Hadassah Medical Center in Jerusalem, and Principal Investigator of BrainStorm's current Phase I/II clinical trial. "Within a few weeks following injection with NurOwn cells, the patient showed dramatic improvement in a variety of functions including breathing, speech, walking, muscular strength, and overall well-being. While we cannot draw scientific conclusions based on the outcome of an individual patient, these results are extremely encouraging."
"We are moved by the remarkable results observed following treatment with NurOwn," said Professor Avi Israeli, BrainStorm's Chairman of the Board. "We are hopeful that we will continue to see this kind of improvement in all the patients participating in our current and future clinical trials."
In January 2012 the Company reported initial safety data from the first four patients in BrainStorm's ALS Phase I/II human clinical trial, indicating that treatment with NurOwn did not present any significant side effects and demonstrated some beneficial clinical effects. After reviewing this safety data, the Hadassah Medical Center ethical committee granted approval for the trial to continue. Interim results for the first 12 patients are expected in July 2012.
BrainStorm expects to expand its ALS clinical development into the United States. Orphan-drug designation for NurOwn has been granted by the US Food and Drug Administration. In addition, the Company has entered into a Memorandum of Understanding with the University of Massachusetts Medical School and Massachusetts General Hospital to begin ALS human clinical trials at these institutions.




About BrainStorm Cell Therapeutics, Inc.
BrainStorm Cell Therapeutics Inc. is a biotechnology company engaged in the development of adult stem cell therapeutic products derived from autologous bone marrow cells and intended for the treatment of neurodegenerative diseases. The Company holds the rights to develop and commercialize its NurOwn™ technology through an exclusive, worldwide licensing agreement with Ramot at Tel Aviv University Ltd., the technology transfer company of Tel-Aviv University. For more information, visit the company's new website at www.brainstorm-cell.com.
Safe Harbor Statement
Statements in this announcement other than historical data and information constitute "forward-looking statements" and involve risks and uncertainties that could cause BrainStorm Cell Therapeutics Inc.'s actual results to differ materially from those stated or implied by such forward-looking statements. Terms and phrases such as "may", "should", "would", "could", "will", "expect", "likely", "believe", "plan", "estimate", "predict", "potential", and similar terms and phrases are intended to identify these forward-looking statements. The potential risks and uncertainties include, without limitation, risks associated with BrainStorm's limited operating history, history of losses; minimal working capital, dependence on its license to Ramot's technology; ability to adequately protect the technology; dependence on key executives and on its scientific consultants; ability to obtain required regulatory approvals; and other factors detailed in BrainStorm's annual report on Form 10-K and quarterly reports on Form 10-Q available at http://www.sec.gov. These factors should be considered carefully, and readers should not place undue reliance on BrainStorm's forward-looking statements. The forward-looking statements contained in this press release are based on the beliefs, expectations and opinions of management as of the date of this press release. We do not assume any obligation to update forward-looking statements to reflect actual results or assumptions if circumstances or management's beliefs, expectations or opinions should change, unless otherwise required by law. Although we believe that the expectations reflected in the forward-looking statements are reasonable, we cannot guarantee future results, levels of activity, performance or achievements.

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  Science & Technology

[digeratidesigns]

We are watching the future of medicine...and it's awesome.

[enyskept]

Oh wow, I missed that...Thanks for pointing that out; it frustrates me when people are quick to thank god for something that was achieved utilizing the methods and tools of science...

[marcus cane]

i would this is true and we would have the chance to correct our bad dna parts and stop diseases that was passed down from a generation before. Even the simplist of things such as pattern baldness would be a outpatient procedure just to name one.

[TUTOPAVEZ]

Are you comparing some sort of god to maths? Really? Come on, i know you are smarter than that.

There is a way of proving math theories: testing. If it works in a 100%, it is a right theory.

And what I was trying to say with "keeping the religion to themselves" was that people should not try to convince another persons, and should tolerate other religions and beliefs or non-beliefs. Moreover, they should keep their religion in their houses or temples. If it sounded different, sorry.

[carvindc400]

Oh, so religious people should keep their beliefs to themselves... I got you completely. Very "democratic" of you. I don't "have to" explain anything to you. It seems that you love to demand things of people. Well... There are some mathematic principles that cannot be proven yet they are used and accepted. So are you going to reject math because a mathematician cannot prove that some of its principles are true? (principle is not the word I wanted, pardon my english)

[TUTOPAVEZ]

I respect other people beliefs with the condition that the person must keep his/her beliefs for himself/herself. If not, why should I?

It is not a stalemate. The person that states that something exists has to prove the existence of it. You cannot prove the opposite. It doesnt make any sense try to prove that something does not exist.

[carvindc400]

You can't prove the opposite either... it is a stalemate then. Respect other people's beliefs and be happy :)

[TUTOPAVEZ]

what makes you think that everything we do comes from a higher source? It is just a logical process. Can you prove that? Is there any evidence? Even a single real story with real facts about it? No.

The one that has to explain why somebody should think that in my beliefe it's you.

No offense intended by the way, I dont want to sound rude, but I couldnt find another way to say it :)

[carvindc400]

and who are you to deny that our intelligence or inspiration to reach these findings do not come from a higher source? ;)

[Dave McNeil]

Did you miss the rabbi's statement at 2:03 then? :)

It never ceases to amaze me when someone who is the recipient of the efforts of the planet's best and brightest are quick to thank god for it.

[enyskept]

I'm wondering when they will attribute this to "god's goodness" or some other religious BULLSHIT...