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F1 ATPase movement

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Uploaded by on Nov 22, 2008

F1 ATPase movement shown by an attached bead seen in a light microscope.

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Science & Technology

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  • @LordStephanos What's imaged in these and similar experiments are beads attached to the molecule of interest. The bead here, while small, is larger than the wavelength of light and so is visualizable with a light microsope. The F1 ATPase spins the bead that is attached to it, which is what the movie is showing. By analyzing the bead's motion and its hydrodynamic drag through the surrounding fluid, one can even figure out the torque the ATPase molecule is applying.

  • @LordStephanos I'm guessing high-speed atomic force microscopy.

  • Light microscope? Molecules can't be seen on light microscope.

  • Awesome!

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