Computational Analysis Methods and Issues in Human Cognitive Neuroscience

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Uploaded by on Jan 14, 2010

Google Tech Talk
January 14, 2010

ABSTRACT

Presented by Bradley Voytek.

There is a massive, relatively uncoordinated effort underway to map out the relationship between brain and behavior. Human neuroimaging experiments abound with approximately 30,000 neuroimaging studies performed in 2008 alone. Most of the data from these experiments are analyzed on an individual desktop or small, local cluster. Neuroimaging data contains information about neural activity in both time and space and can easily exceed 1GB per subject. In order to analyze the functional properties of neuronal networks these data can be decomposed in a variety of ways (behavioral condition, principal and independent components, phase and frequency components, graphs and digraphs, etc.). This exponentially increases analysis time and database sizes creating bottlenecks in the analysis work flow. I will discuss a variety of neuroimaging methods in terms of the sources of the signals measured, what these signals actually inform us about how the brain gives rise to cognition and behavior, and how this information can inform medical diagnosis and treatment. Furthermore I will highlight how advances in computational processing have improved data analysis and discuss the computational roadblocks that impede research progress.

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Top Comments

  • Many neurons fire what are referred to as "all or none" action potentials, which are brief electrical impulses that result in the release of neurotransmitter into the synapse. When these transmitters bind to the next neuron they can affect the electrical potential of the next neuron. This gives the impression of them being binary. However there are many "analog" neurons, and the resting potential of the extracellular membrane can affect the probability of an action potential.

  • I toned down the topic quite a bit out of fear that it would be more technical without a good background. Then I ran out of time. If anyone would like to more on the technical side of things, please, feel free to email me.

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  • informative video! i lab it

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  • i enjoy listening to your talks. i'm worried that i may develope alzhimer or dementia. my memory problems started in high school. any suggestion about what i can do to help? i write every thing down, i talk to at least 40 people every day not alway the same people so i use their personaly to remember their name. can vititams help?

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