DNA Replication (Very realistic 3D animation)

Extremely cool video. In ATP (for example) the triphosphate is attached to the 5'. The connection is 5' to 3' driven by the separation of the phosphate. It could not happen the other way.

I'm not sure why both strands can't be copied forward. Apparently the physics of protein formation preclude that from occuring.

DNA is only synthesized during replication from the 5' to 3' direction. In the leading strand, this direction is toward the replication fork. In the lagging strand, this direction is away from the fork, so the synthesis is discontinuous.  It's due to the chemistry of the nucleotides and how DNA polymerase can synthesize DNA only onto the 3' end of a nucleotide. Protein formation is not involved.

Because one strand runs from 5' to 3' and the other runs from 3' to 5'. That is why the DNA double helix is antiparallel.

lol i saw this in my biology class xD

wait.. what's going on....?

too fast don't follow at all @.@

how do they figure this stuff out? its so tiny

can someone please explain to me what a osaki fragment is?

oaski frag. = the bursts of DNA being copied on the lagging end (the end that keeps getting looped around).

it's very easy to see this in a procaryote organism that has a relatively small genome. i'm not too sure but i think scientists were able to see this happening around 1960's.