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Fructose increases food intake, whereas glucose decreases food intake

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Uploaded by on Apr 9, 2009

http://fatnews.com/ Hi, this is Larry Hobbs @ FatNews.com.
LarryHobbs@fatnews.com

Fructose increases food intake is because fructose metabolism requires an enzyme that depletes ATP, whereas, glucose increases ATP, and therefore decreases food intake.

This according to a great new study from researchers at Johns Hopkins University School of Medicine in Baltimore, Maryland, USA.

Hi, this is Larry Hobbs @ fatnews.com

larryhobbs@fatnews.com

They also noted that the rise in consumption of high-fructose corn syrup and sweeteners parallels the rise in the obesity epidemic

REFERENCE

Lane MD, Cha SH. Effect of glucose and fructose on food intake via malonyl-coa signaling in the brain. Biochem Biophys Res Commun. 2009 Apr 24, 382(1):1-5.

AUTHOR'S CONTACT INFORMATION

M. Daniel Lane
Department of Biological Chemistry
The Johns Hopkins University School of Medicine
512 Wood Basic Science Building
725 N. Wolfe Street
Baltimore, MD 21205, United States
dlane@jhmi.edu
+1 410 955 0903 Fax

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Uploader Comments (larryshobbs)

  • Is your omission of the similarities between sucrose vs HFCS deliberate?

  • They did not talk about sucrose in the paper, so I left it out.

    However, the research suggests to me that there is a difference.

    20 or 30 years ago, there were several reports in the medical literature that people who ate the most sugar were the leanest, and those who ate the most fat were the fattest.

    Hard to believe, but true.

    This was back when sugary foods mostly contain sucrose.

    Sucrose is 50% glucose and 50% fructose.

    The glucose may have offset the effects of fructose.

    Larry Hobbs

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All Comments (4)

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  • I recommend you also watch "Sugar: the bitter truth" by Dr Lusting on YouTube. It explains that Fructose, a major reason for obesity today, has been used by food companies as a sweetener instead of Sucrose (table sugar) because it is cheaper! There have been other studies that establish a link between high consumption of Fructose with cancer. Some studies have also shown that Hyperglycaemia, which has a direct relationship with elevated sugar and insulin spikes, also leads to g

  • Sean is right. Sucrose and HFCS are essentially the same thing. There is HFCS 55, which is mostly used in soft drinks, and HFCS 42, which is what you'll find in all the other processed junk. The number corresponds to the percentage of fructose relative to glucose. HFCS 55 is 55/45, HFCS 42 is 42/58.

    The problem is that fat, an appetite suppressant, has been removed from processed foods and replaced with HFCS or sugar. The result: people get fatter, yet remain hungry, as you said.

  • Sucrose, table sugar, honey, etc. are all chemically just about the same as High Fructose Corn Syrup.

    They're all equally as bad. The major problem is that high fructose corn syrup got put in almost *everything* cause it's easy, and cheap.

    If you want to avoid the negative health effects of High Fructose Corn Syrup, you'll also have to avoid table sugar, evaporated cane juice, honey, sucrose, basically anything that contains a high level of fructose.

    Fructose is the problem, not just HFCS

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