Fluorescence Imaging of Eukaryotic Endoplasmic Reticulum

This video shows a brief, real time stream of a live Chinese hamster ovary (CHO) cell treated with a special fluorescent dye known as a squaraine rotaxane. The movements of the cellular structures in this video are suddle so you may have to view it several times to catch their dynamics. This particular version of the dye specifically partitions into the membranes of these CHO cells, allowing for detailed imaging of this cellular structure. This dye, along with other variants of it, are desiged, synthesized, and studied by Bradley Smith's research lab at the University of Notre Dame.

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Tags:

• fluorescence
• imaging
• cell
• biology
• endoplasmic
• reticulum
• squaraine
• rotaxane
• dyes