DNA Central Dogma Transcription and Translation
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All Comments (20)
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Thanks for making this!
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Thanks! ;)
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good explained
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thank you!
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This helped so much more than my professors did over the past semester in gen bio And biochem. Thank for posting this:)
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omg thank you!!
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Even though I am in advanced molecular biology now, I tend to always forget the basics! Great review!!
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very good, better than that goon in the pink shirt and yellow tie. Cheers
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Superb
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does the suger or the phosphate connect to the a t and c g
PureDomination48 2 years ago
@PureDomination48 I have a video on DNA nomenclature that should help clrify that question.
gkpeter 2 years ago
Very well explained. I just have 2 questions. 1) How does the RNA polymerase know where to start and stop transcribing and 2) If there are 2 start codons before the next stop in the mRNA does that mean you get overlapping protein sites?
mtanti87 2 years ago
In eukaryotic cells, transcription is normally thought to originate at a TATA box. Basically a sequence that the polymerase or proteins that attract the polymerase can bind to. I believe there is then a termination sequence also. As for translation, in eukaryotic cells, it looks for a Kozak sequence to initiate translation.
gkpeter 2 years ago
You didn't mention any Kozak sequence in your video, though from what I found, it contains the start codon. So is it possible to get 2 TATA boxes or Kozak sequences before the next termination sequence or stop codon? Would that be overlapping genes / protein templates?
Thanks
mtanti87 2 years ago
The goal of the video is to basic, therefore I did not mention TATA boxes and Kozak sequences. Theoretically, two kozac sequences could be present, however, I don't know if that is actually the case. It is more likely that alternative splicing would be used to obtain different protein products.
gkpeter 2 years ago