Chromosome (telephone parody)

EDIT: Lyrics can be found below.
This is 'Chromosome', the educational parody of Lady Gaga's 'Telephone' music video. It is a project that I directed this summer in the hopes of making science fun and interesting for students. Thank you to all of my talented friends for helping make this video possible! I hope you enjoy it and remember everyone, science is fun!

Lyrics:
Hello? Hello? Baby, you called. I can't hear a thing.
I have got not service in the laboratory.
I have got no time for talking. Baby, can't you see?
I am trying to study some biochemistry.

When the chromosomes condense then we call it prophase.
And when they line up then it is called metaphase.
When they pull apart then we call it anaphase.
And when they divide into two cells that is telophase.

Stop calling. Stop calling. I don't wanna talk anymore.
I have a test that I am studying for.

GTACCCGTAGT
Neucleotides are
CATGGGATCA
They go
TACATGTCT
Neucleotides are
ACTTCGGAATA

DNA wrapped around histones.
It's all in the chromosome.
Everything in your genome:
It's all in the chromosome.

And when those cells explode they call it apoptosis.
Different than necrosis. Not caused by osmosis.
It's dangerous when the cell begin undergoing anoikis.
Then there's metastasis. Cell death is so tasteless.

DNA is simple if at first you only think,
That you have a purine paired with a pyrimidine.
The sugar-phosphate backbone holds all the bases
Which is twisted around like a spiral staircase.

Copying, copying like in vivo but much faster.
I got my genes from the lab thermocycler.

• Category

  Education

[wildmntflower]

Good job ladies! Instead of picking over the tiniest details, maybe those of us in the field should just applaud what is really a very artful way to get students thinking about the basics of biology. As someone with a degree in Cellular/Molecular Biology, I'm not offended by the word choice; I'm just thrilled the song writer was able to fit so many of the terms that were accurately utilized into a pop song. If this song inspires any young biologists, they'll learn the exact definitions later.

[Marcus Tio]

Study of chromosomes is under Cell Biology, not Biochemistry.

[KevinMurnan]

Actually, genetics, cell biology, and biochemistry overlap so much that you really can't designate one specific label. Honestly, it's why most PhD programs now offer interdisciplinary degrees. As for chromosomes specifically, it's obviously genetics, with epigenetic regulation governed by the principles of biochemistry, as part of cell biology.

[Shabab Rahman]

do you know how to reply to comments?

[idaLAduce]

i think i would have got more of the gist, if the ladies would have accepted themselves not having a singing voice.

[ThePedja123]

Can I have Prophase's telephone number? :D

[Marcus Tio]

I didn't fail O Level Biology. I scored a B3 although I didn't put in much effort in preparation for it. I also scored B3 in O Level Physics but I scored A2 in O Level Chemistry.

[burgel18]

fail

[Marcus Tio]

OK. I don't know, because I only studied Biology up to O Level. I am not interested in A Level H2 Biology, so I chose H2 Physics.

[metalhead33]

Biochemistry is the essence of cell biology, and all biology that is!

[nobelphoenix]

Probably they are talking about "TTGACA" consensus sequence. It is a bacterial promoter region paired with Pribnow sequence (TATAAT) that initiates bacterial transcription.

Although in the genome they are not always ideally sequenced as "ttgaca" or "tataat", they should roughly resemble these sequences.

In their case: caTggGAtCA

[leonidas1993]

C=cytosine

A=adenine

T= thymine

G=Guanine

those are bases of the DNA in RNA T changes to U (uracil)