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Melanocytic Melanoma Mimics

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Uploaded by on May 2, 2010

Dr. James L. Campbell Jr., MD discusses Melanocytic Melanoma Mimics. See more at http://www.dermnet.com PLEASE RATE AND COMMENT!!!
Melanocytic melanoma mimics




Blue Nevi




Blue nevi are benign melanocytic nevi with nevus cells located deep within the dermis. Their blue to black coloration may suggest melanoma. Blue nevi

are sharply defined, uniform in color, and are stable in size or appearance over many years.




Combined Nevus




Combined nevus refers to the combination of a blue nevus deep in the dermis

associated with an overlying benign junctional, compound or intradermal nevus. Combined nevi are usually solitary and are often asymmetric with focal dark pigmentation. This presentation

suggests melanoma though the patient has not noted any change in the lesions appearance.




Traumatized Nevi




Traumatized nevi may be partially avulsed and/or have hemorrhagic crusting

suggesting ulceration. Patients are usually aware of the trauma. Nevi previously partially removed either by trauma or biopsy can develop recurrent nevus phenomenon over several weeks to months.

Melanocyte hyperplasia develops superficial to the scar resulting in uneven pigmentation and irregular outlines as pigment extends into the surrounding skin-quite suggestive of melanoma.

Recurrent nevus phenomenon can resemble melanoma histologically, as well. The history of trauma or biopsy along with review of the original biopsy helps exclude a diagnosis of melanoma.

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