Generic Lexapro

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Escitalopram (trade names Lexapro, Cipralex, Seroplex, Lexamil) is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is approved by the U.S. Food and Drug Administration (FDA) for the treatment in adults with major depressive disorder, generalized anxiety disorder, social anxiety disorder , or panic disorder. Escitalopram is the S-stereoisomer (enantiomer) of the earlier Lundbeck drug citalopram, hence the name escitalopram. Escitalopram is noted for its high selectivity of serotonin reuptake inhibition and has side effects typical for the SSRI class.

Despite the similarity of escitalopram and citalopram, preclinical as well as various clinical studies (including double-blinded studies) have shown differentiated effects of citalopram and escitalopram, as well as a clinical superiority compared with a variety of other SSRIs, such as paroxetine, especially in severely depressed patients. A head-to-head comparison of escitalopram with duloxetine found escitalopram to be both more tolerable and more effective. Compared with venlafaxine and sertraline, escitalopram was shown to have similar efficacy.

According to a meta-analysis of 12 new-generation antidepressants, escitalopram and sertraline are the best in terms of efficacy and acceptability in the acute-phase treatment of adults with major depression; however, sertraline may be a better choice because of the lower cost.

Dosage usually ranges from 10 mg/day ranging to a maximum recommended dose of 20 mg/day. For elderly people or people with GI problems, the maximum recommended dose is 10 mg/day

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• Lexapro
• Escitalopram
• antidepressant
• selective
• serotonin
• reuptake
• inhibitor
• SSRI