Open fetal surgery: past, present and future

Timothy Crombleholme, MD, is a recognized leader in the field of fetal surgery and pediatric surgery. He has been named the 2011 president of the International Fetal and Surgery Society.

Prior to starting the Fetal Care Center at Cincinnati Children's Hospital Medical Center in 2004, he was part of the Center for Fetal Diagnosis and Treatment at Children's Hospital of Philadelphia (1996 to 2004). Previously, he was director of the Fetal Treatment Program at the New England Medical Center in Boston, MA (1993 to 1995).

A graduate of Tufts University School of Medicine, Boston (1984), Dr. Crombleholme was a surgical resident and chief resident at the University of California at San Francisco (1984 to 1991), and a chief resident in pediatric surgery at The Floating Hospital for Infants and Children at the Tufts-New England Medical Center in Boston, MA (1991 to 1993). He trained under Michael Harrison, MD, who is widely recognized as the founder of fetal surgery.

In addition to his surgical expertise, Dr. Crombleholme is active in clinical and laboratory research. He established the Center for Molecular Fetal Therapy as the basic research laboratory component of the Fetal Care Center of Cincinnati.

Dr. Crombleholme's current clinical investigations include a National Institutes of Health funded multicenter trial to determine the best treatment for twin-twin tranfusion syndrome / TTTS and research on new techniques for open fetal surgery and fetoscopic surgery. His laboratory research includes NIH-funded studies of gene therapy in tissue repair, fetal gene therapy and the role of the fetal fibroblast in fetal wound healing.


Research

- Gene Therapy in Tissue Repair
- Fetal Gene Therapy
- Role of the Fetal Fibroblast in Fetal Wound Healing
- Fetal Gene Therapy in lamb and mouse models of GM1 gangliosidosis
- Fetoscopic Surgery
- Fetal Tracheal Occlusion

Category:

Science & Technology

Tags:

• fetal
• surgery