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Using the WHO criteria, 30% of Caucasian postmenopausal women in the US have osteoporosis, and 54% have osteopenia. The prevalence of low bone mass increases with age. Using the WHO definition of osteoporosis, the prevalence in the US of osteoporosis in Caucasian postmenopausal women based on the lowest bone mass at any site is estimated to be 14% of women aged 50-59 years, 22% of women aged 60-69 years, 39% women aged 70-79 years, and 70% women aged 80 years or greater(ref 3).
Factors Influencing Bone Mass
Peak bone mass occurs for both men and women by the early thirties. Genetic factors play the greatest role in determining peak bone mass, but there are clinically significant contributions from nutrition, drug exposures, endocrine health following puberty, and weight-bearing status (ref 4).
For example, most teenagers and young adults do not receive the Recommended Daily Allowance (RDA) for calcium of 1200 mg. Smoking and excessive alcohol use contribute to low bone mass. Systemic glucocorticoid use of 7.5 mg daily or greater impairs bone formation.
Phenytoin and other anti-seizure medications impair vitamin D metabolism. Oligomenorrhea and amenorrhea cause accelerated bone loss, as do hyperthyroidism or over-replacement of thyroxine supplementation such that the serum TSH is suppressed. Immobility is associated with thinning of the bone from lack of weight-bearing forces.
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I got a very terrible weight problem , but I am not fat yet slim . I am 1.77m tall and weighs 79kg , 5 years ago , i was 65 kg . Like I said , I don't look fat nor I do carry weights or have huge mass , I look slim or almost skinny . What is my problem ?
azmidasimin 11 months ago