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FDA Approves Depressant Drug For The Annoyingly Cheerful

TheOnion TheOnion·845 videos
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Uploaded on Feb 12, 2009

Made by Pfizer, Despondex is the first drug designed to treat the symptoms of excessive perkiness.

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Top Comments

  • Okami Amaterasu

    Cool beans.

    · 129

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  • BockClock

    fucking perfect execution of the f-bomb there, was not expecting it

    · 61

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Video Responses


All Comments (3,366)

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  • Jigglydorf Puffcroft

    Corn syrup, white bread and a total lack of exercise. Pizza is a good substitute for white bread.

    ·

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  • Tiny Speck

    finally.

    ·

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  • DDaniel20067

    Fuck yeah!

    

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  • squamish4244

    I have met several people who have transformed themselves through meditation practice...it is surreal how stable they are.

    ·

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    in reply to wiadroman (Show the comment)
  • wiadroman

    Agreed, as the old adage goes "only children and idiots are always happy", those are not fake.

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    in reply to squamish4244 (Show the comment)
  • mrboomvadaboom

    Oh hey look, my original version.

    ·

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    in reply to Okami Amaterasu (Show the comment)
  • ECL28E

    (Insert Pinkie Pie joke here)

    ·

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  • Matt Dolloff

    Rob Lowe's character on Parks & Recreation could use this.

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  • MIchael Miller

    I know right?

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  • kztar621

    I know people that need this.

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