FDA Approves Depressant Drug For The Annoyingly Cheerful
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Uploaded on Feb 12, 2009
Made by Pfizer, Despondex is the first drug designed to treat the symptoms of excessive perkiness.
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Top Comments
Okami Amaterasu 10 months ago
Cool beans.
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BockClock 10 months ago
fucking perfect execution of the f-bomb there, was not expecting it
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Video Responses
All Comments (3,366)
Jigglydorf Puffcroft 5 days ago
Corn syrup, white bread and a total lack of exercise. Pizza is a good substitute for white bread.
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Tiny Speck 1 week ago
finally.
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DDaniel20067 1 week ago
Fuck yeah!

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squamish4244 2 weeks ago
I have met several people who have transformed themselves through meditation practice...it is surreal how stable they are.
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wiadroman 2 weeks ago
Agreed, as the old adage goes "only children and idiots are always happy", those are not fake.
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mrboomvadaboom 2 weeks ago
Oh hey look, my original version.
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ECL28E 3 weeks ago
(Insert Pinkie Pie joke here)
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Matt Dolloff 4 weeks ago
Rob Lowe's character on Parks & Recreation could use this.
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MIchael Miller 1 month ago
I know right?
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kztar621 1 month ago
I know people that need this.
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