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Medical School Pathology, Chapter 7l

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Uploaded by on Oct 6, 2008

Medical School Pathology, Chapter 7l: Neoplasia

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  • Vinyl chloride = hemangiosarcoma in liver?

  • i very easily could have goofed, here is the facts:-->In the early 1970s, Dr. John Creech and Dr. Maurice Johnson were the first to clearly link and recognize the carcinogenicity of vinyl chloride monomer to humans when workers in the polyvinyl chloride polymerization section of a B.F. Goodrich plant near Louisville, Kentucky, were diagnosed with liver angiosarcoma also known as hemangiosarcoma, a rare disease

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  • Source: ^ Jamshidi A, Hunter S, Hazrati S, and Harrad S (2007). "Concentrations and Chiral Signatures of Polychlorinated Biphenyls in Outdoor and Indoor Air and Soil in a Major UK. Conurbation". Environmental Science Technology 41 (7): 21532158. doi:10.1021/es062218c.

  • Initiators: The cell that starts the development of cancer. The promoter comes after the initiator. Just think that it "promotes" like when you promote a product so it sells. There is the product (initiator) already and you just want to make sure the product really sells and survives in the market so you promote by whatever means (ad, by word of mouth), etc.

  • whats the diff bw promoters and initiators?

  • i belive he confused PCBs with CFCs ..................pcbs are way too heavy to be arosolized into the atmosphere

  • thanks

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