Alert icon
We're changing our privacy policy. This stuff matters.  Learn more  Dismiss

32. Stereotopicity and Baeyer Strain Theory

Loading...

Sign in or sign up now!
Alert icon
Upgrade to the latest Flash Player for improved playback performance. Upgrade now or more info.
1,897
Loading...
Alert icon
Sign in or sign up now!
Alert icon
There is no Interactive Transcript.
Ratings have been disabled for this video.

Uploaded by on Sep 18, 2009

Freshman Organic Chemistry (CHEM 125)

Why ethane has a rotational barrier is still debatable. Analyzing conformational and configurational stereotopicity relationships among constitutionally equivalent groups reveals a subtle discrimination in enzyme reactions. When Baeyer suggested strain-induced reactivity due to distorting bond angles away from those in an ideal tetrahedron, he assumed that the cyclohexane ring is flat. He was soon corrected by clever Sachse, but Sachse's weakness in rhetoric led to a quarter-century of confusion.

00:00 - Chapter 1. What is the Source of the Rotational Barrier in Ethane?
06:34 - Chapter 2. Topicity, Reactivity Difference, and Enzyme Specificity
27:49 - Chapter 3. Baeyer's Strain-Induced Reactivity Theory: Assumptions and Weaknesses
36:42 - Chapter 4. Sachse's Muddled Insights on Cyclohexane

Complete course materials are available at the Open Yale Courses website: http://open.yale.edu/courses

This course was recorded in Fall 2008.

Category:

Education

Tags:

License:

Standard YouTube License

All Comments

Adding comments has been disabled for this video.

Alert icon
0 / 00Unsaved Playlist Return to active list
    1. Your queue is empty. Add videos to your queue using this button:
      or sign in to load a different list.
    Loading...Loading...Saving...
    • Clear all videos from this list
    • Learn more