Early Puberty in Girls and the Role of Environmental Factors

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Uploaded by on May 16, 2011

Environmental exogenous estrogens, otherwise referred to as xenoestrogens, are endocrine disruptors structurally similar to estrogens. Xenoestrogens are clinically significant because they can mimic the
effects of endogenous estrogen and thus have been implicated in early or precocious puberty and other disorders of the reproductive system. Xenoestrogens can be found in pesticides, flexible plastics, flame
retardants, interior lining of canned foods, various cosmetics and numerous other products. Xenoestrogens are thought to cause many detrimental health effects such as precocious puberty in
girls. There is a concerning steady increase in exposure to a wide variety of xenoestrogens in the industrial world. Further research is needed to assess the impact of these compounds on pubertal development.

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