Storage Lesions in Cellular Blood Components

While we often talk about getting better with age, this generally applies only to fine red wines. Even then, theres a limit to improvement before deterioration wins out. But what about blood? In this video from the University of Washingtons Laboratory Medicine Grand Rounds series, Dr. James AuBuchon, president and CEO of the Puget Sound Blood Center explains how biochemical changes in platelets and red cells with ex vivo storage are many and varied, including surface changes as well as reductions in functional capabilities. The extent to which these changes reduce the effectiveness of transfusions, or possibly even harm transfusion recipients, remains unclear. Retrospective clinical studies have certainly raised concerns about old blood, but prospective trials have failed to corroborate the incrimination. So whats best for the patient?

To see more videos from the University of Washington visit uwtv.org.

Category:

Education

Tags:

• health
• medicine
• education

[SuperEmitube]

too long to watch sorry :(