Make Phenol (carbolic acid) from Aniline

In this video we make Phenol from Aniline via the Sandmeyer reaction.

Phenol and its vapors are corrosive to the eyes, the skin, and the respiratory tract. Repeated or prolonged skin contact with phenol may cause dermatitis, or even second and third-degree burns due to phenol's caustic and defatting properties.Inhalation of phenol vapor may cause lung edema.The substance may cause harmful effects on the central nervous system and heart, resulting in dysrhythmia, seizures, and coma.The kidneys may be affected as well. Exposure may result in death and the effects may be delayed. Long-term or repeated exposure of the substance may have harmful effects on the liver and kidneys." There is no evidence to believe that phenol causes cancer in humans.Besides its hydrophobic effects, another mechanism for the toxicity of phenol may be the formation of phenoxyl radicals.

Chemical burns from skin exposures can be decontaminated by washing with polyethylene glycol, isopropyl alcohol, or perhaps even copious amounts of water. Removal of contaminated clothing is required, as well as immediate hospital treatment for large splashes. This is particularly important if the phenol is mixed with chloroform (a commonly-used mixture in molecular biology for DNA & RNA purification from proteins).

Category:

Science & Technology

Tags:

• Sandmeyer reaction
• phenol
• make phenol
• Aniline
• Reactions aniline
• carbolic acid
• Hydroxybenzene

[myst32YT]

phenol.... 

[myst32YT]

phenol...

[thegreatwoodlife]

I've seen what both of these chemicals can do. Aniline will remove the oxygen out of your blood. Even a small drop on your body can kill you. Phenol smells like soar throat medicine and damage your nerve system.

I've never been exposted to Aniline, though I did have a friend nearly die from a drop that spilled on his boots and soaked through to his skin. I did have a rather nasty experience with Phenol under a pressurized tank.

Amazing this chemical is a byproduct of refining crude oil.

[myst32YT]

@thegreatwoodlife Aniline?? are you sure your not confusing this with something else. It's DERMAL (LD50) is 1400 mg/kg [Rat]. Granted I would not want it on me. We used Aniline in our organic chem lab at college years ago... I am pretty sure they would not let students handle something that would kill you if a drop got on you. The MSDS states "Slightly hazardous in case of skin contact ". Dimethylmercury will kill you if a drop gets on you and it will soak through rubber gloves.

[LazyPL]

How to make phenol from salicylic acid?

[myst32YT]

@LazyPL Ok, this works.... just not very well.... I will put the video on it later...

[ElJozir]

@thegreatwoodlife Aniline attaches itself on your red blood cells making oxygen absorption impossible a human body can't brake down aniline.

A large drop Phenol will kill you. Its melting point is 40° a bit above the human body temperature in contact with skin it gives white burns with red around the contamination zone. It disables the kidney functions.

[shiftgood1]

con....last time I promise...to sulfunize benzene you gotta heat the benzene in flask with an upright condenser. The heated benzene has a little con. H2SO4 in it and as it heats (a long time.... :( it will not evaporate as it cools and goes back down to the flask. Hense; reflux heating for long periods without loosing slovent. (heat about 4 to 6 hours)

[shiftgood1]

....try sticking to formula, I guess? Maybe you can use potassium hydroxide Looking up this stuff a SAFE way may take days. Tiny mistake use a LARGE PAINT CAN as you dump your your molten sodium hydroxide to the sufinized benzene. Again; a LARGE PAINT CAN with your relatively small amount of sufinized benzene. It's is gonna splatter. Do outside. Ware thick gloves and thick arm and protection for your face. P.T. Alpha and Omega for Phenol plastics....etc....Box Club rules.... too.

[shiftgood1]

Please please please forgive me for being verbose. I forgot to say after you put the molten sodium hydroxide to the SULFINIZED BENZENE, (and it WILL SPATTER BADLY -wear thick gloves and arm protection-but you get LOTS OF PHENOL), do an acid work up, by very dilute sulfuric acid into latter via crunching up your "rocks" from the molten job... crystalize in cold place with fan on it, if no crystals- add more H2SO4. in luie of the latter BOX CLUB RULES , 44mph on car, say greeting, ETC... call me.

[OMKBialystok]

Can I use potassium nitrate, not sodium nitrate?

[98JMA]

Do you own a professional ice machine?

[shiftgood1]

Makeing phenol is one of the highest accomplishments one could ever achieve in the 21st century!!!!!! PTL Highest Spirit/

(I speak in luie of part time work only, 40 no more speed, publish eerywhere, say the latter as greeting fpr love of others, eternal life, Future Consciousness Unit for unravelling disapping stuff, contact me for Spiritual abilities, and no fears of things or people, write things down. Sounds bad for a person to say this but it is necessary. I have done this for 10+ years).

[shiftgood1]

...cont.... I speak in addition to priseing the Alpha and Omega Spirit Point, THE BOX CLUB rules, 44mph max sticker on vehicles, 25 hours work no more, say the latter at all stores as "greeting," I think Im the guy you wanna meet with and publish the "Greeting" on and off media. It is a Large Quantum World. AGain, THANK YOU FOR YOUR contacting me about the latter only. :O) Oh yes, LOVE comes from appreciating everything like this guys Phenol way as well as mine

[shiftgood1]

Phenol VIA Benzene 1. Benzene to "Sufo.-benzene-" do HEAT benzene first THEN add some con H2SO4. But not too much H2SO4 It will REVERSE "sulfonizing" 2."Sulfo-benzene" to sodium pheoxide | Do this in tiny paint can of molten SOD. HYDROX added to tiny paint can of sulfoben. BUT LOOK OUT! It is GONNA SPATTER-YET WORKS :o) 3. sod-.phenox. acidfication is done via a LITTLE dilute sulferic acid to Sodphenox. and stir The thick stuff SOULD crystalize Phenol P! I say all this in luie of ...cont...

[LOL64431]

you lost me after 2:00