DangeRAS

A Lesson in Biology about the Development of Cancer

Produced by college students with very minimal talent as a tool to teach others about how cancer spreads at the molecular level. Two of the most common methods (proto-oncogenes: Ras and tumor suppressors: p53) are described.

Lyrics:

Cell I can see
One mutation
Mutating
All over the body
I can see it
And cant stop Ras
Always active
No GTP hydrolysis
Watch out
Ive seen its type before
That Ras is so dangerous
That Ras is so dangerous
Its Mutant causes cancer
Ive seen its type before
Rass so dangerous
That Ras is so dangerous
Its Mutant Causes cancer, yeah.

Cancer cells, like John McCain
Are mavericks they cant be slain
Ignoring signals from other cells
Is what Im saying ringing a bell?
Unchecked proliferation
One amino acid substitution
Ras is now an oncogene
A defective regulatory machine
Ability to migrate through
The cell
Second key trait of how
Cancer raises hell
Back to Ras- a GTPase
Activates MAP triple kinase
Activated by tyrosine
Man, that mutant Ras is mean

Ras definitely causes cancer a lot
But its not the only one, believe it or not
Tumor suppressor genes also work
To bring cancer, those stupid jerks
Two mutations are needed
To get this evil cancer seeded
P53 stops stopping terrible mutations
Which leads to mass cell proliferation
Then the cell divides when it shouldnt
Nuke was possed to get STOP signal and it couldnt

Then those cells ignore everything
All the problems that will bring
Soon comes along angiogenesis
Stealing blood vessels creates such a mess
Problems start with unlimited replication
Metastasis and tissue invasion
Hopefully, the time will come
When cancer wont bother anyone
Until then well study and wait
Dreaming about that special date

Category:

Comedy

Tags:

• cancer
• RAS
• proto-oncogenes
• p53
• tumor suppressors

[Garblod]

fuckin dicks I cant understand shit! what about a normal explanation????! Fuck u!

[MsGorgeousGeek]

HAHAHAHA...THANKS lol that helped

[smunoz08]

dude this is... just.... weird! But i have to say that i did unsderstand more about ras