Scientist Acts Out Nicotinic Acetylcholine Receptors

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Uploaded by on Jan 2, 2007

She describes the binding of nicotine to receptors, while our friend laser points at her

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  • BTW, drugs with muscarinic actions may stimulate nicotinic receptors when given at high concentrations, & vice versa.

  • Nicotine, a substance present in tobacco. Muscarine, derived from a poisonous mushroom named, Muscarina.

  • And thus they were named so. And it's the same with muscarinc receptors which show a higher affinity for Muscarine than Ach and Nicotine.

  • @frenchman123 Nicotinic receptors show a higher affinity for Nicotine than Ach, t

  • @eche05 regardless of what SHE knows. The body does not produce such a thing as "nicotinic acetylcholine", nicotinic is only an adjective used to describe a specific subtype of acetylcholine receptors that was discovered because nicotine binds to it...

  • I don't think she understands the body naturally produces nicotinic acetylcholine which regulates acute somatic (and autonomic) muscular movements. Tha'ts why anticholinergics like belladona or diphenhydramine produces ataxia in individuals.

  • this individual cannot possibly be an authority on nicotinic acetylcholine receptors, they didn't even mention that A: acetylcholine itself is the molecule that the receptors are designed to respond to B: nachrs are not closed before agonist binding, they are just more likely to be closed and flicker between open and closed states and C: nicotine will desensitise some receptors.

  • wtf is she talking about?

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