@eche05 regardless of what SHE knows. The body does not produce such a thing as "nicotinic acetylcholine", nicotinic is only an adjective used to describe a specific subtype of acetylcholine receptors that was discovered because nicotine binds to it...
I don't think she understands the body naturally produces nicotinic acetylcholine which regulates acute somatic (and autonomic) muscular movements. Tha'ts why anticholinergics like belladona or diphenhydramine produces ataxia in individuals.
this individual cannot possibly be an authority on nicotinic acetylcholine receptors, they didn't even mention that A: acetylcholine itself is the molecule that the receptors are designed to respond to B: nachrs are not closed before agonist binding, they are just more likely to be closed and flicker between open and closed states and C: nicotine will desensitise some receptors.
BTW, drugs with muscarinic actions may stimulate nicotinic receptors when given at high concentrations, & vice versa.
TheHonestMan1213 6 days ago
Nicotine, a substance present in tobacco. Muscarine, derived from a poisonous mushroom named, Muscarina.
TheHonestMan1213 6 days ago
And thus they were named so. And it's the same with muscarinc receptors which show a higher affinity for Muscarine than Ach and Nicotine.
TheHonestMan1213 6 days ago
@frenchman123 Nicotinic receptors show a higher affinity for Nicotine than Ach, t
TheHonestMan1213 6 days ago
@eche05 regardless of what SHE knows. The body does not produce such a thing as "nicotinic acetylcholine", nicotinic is only an adjective used to describe a specific subtype of acetylcholine receptors that was discovered because nicotine binds to it...
frenchman123 1 year ago
I don't think she understands the body naturally produces nicotinic acetylcholine which regulates acute somatic (and autonomic) muscular movements. Tha'ts why anticholinergics like belladona or diphenhydramine produces ataxia in individuals.
eche05 3 years ago
this individual cannot possibly be an authority on nicotinic acetylcholine receptors, they didn't even mention that A: acetylcholine itself is the molecule that the receptors are designed to respond to B: nachrs are not closed before agonist binding, they are just more likely to be closed and flicker between open and closed states and C: nicotine will desensitise some receptors.
brummiephil3 4 years ago
wtf is she talking about?
bl4cksm0k3 4 years ago 2