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The architecture of adaptation

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Uploaded by on Aug 10, 2009

Cells and organisms need to respond to external stimuli, but then reset, in a process called adaptation, so they can be prepared to respond to further perturbations. Biochemical pathways can be characterized as having discrete kinds of topologies or architectures. Dr. Wendell Lim and his colleagues explain how they systematically probed a number of possible biochemical architectures to determine the ones that are most effective for achieving adaptation.

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