Attack of amines on aldehydes and ketones (2)

Organic chemistry: Nucleophilic attack by amines on aldehydes and ketones to form imines (category 3) and enamines (category 4). Wolff-Kishner reduction. Nucleophilic addition of hydrogen cyanide to aldehydes and ketones (category 1). The Wittig reaction (category 3); how to make phosphorus ylides

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(1) Primary, secondary, and tertiary amines
(2) Nucleophilic attack by primary amines on aldehydes and ketones to form imines (a category 3 reaction)
(3) Continued
(4) Nucleophilic attack by secondary amines on aldehydes and ketones to form enamines (a category 4 reaction)
(5) Continued
(6) Continued
(7) The Wolff-Kishner reduction
(8) Problems
(9) Continued
(10) Nucleophilic attack by hydrogen cyanide on aldehydes and ketones
(11) The Wittig reduction
(12) Continued
(13) How to make phosphorus ylides

Category:

Education

Tags:

• organic
• chemistry
• aldehyde
• ketone
• nucleophilic
• attack
• amine
• imine
• enamine
• wolff-kishner
• reduction
• wittig
• reaction
• phosphorus
• ylide
• cyanide
• mechanism

[mh43460]

@guzzbar actually it is oxygen bonded to C and H

its neutral

in next step at ,where it gives its pair of electon to H+ it becomes +ve 3:47

[baydoun1991]

i hate the asterisk idea, because it just adds more rubbish to the atom! i wish you havent used it.

[jjsearson]

why do gringuard reactions stop at category 1 reactions?

why does the O not leave and a second gringuard attack?

[guzzbar]

nevermind... :)

[guzzbar]

y is there a negative sign on the oxygen at 3:10 if it is attached to the carbonyl carbon and a hydrogen? thanks

[BluephishBnJ]

Isn't use if equilibrium arrows dependent on pKa's and ease of reversibility of each reaction?...