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RNA Interference (RNAi)

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Uploaded by on Mar 29, 2008

RNA Interference (RNAi) mechanism in worms and plants.

Created for Nature Reviews Genetics by Artikek Studios Inc.
Copyright 2006. All right reserved worldwide.

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Science & Technology

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Standard YouTube License

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Top Comments

  • RISC : RNA induced Silencing Complex, and not RNA interference Silencing complex you dummy !!!!!!

  • @redSHIFT69 nerds made youtube... and the internet. GO NERDS!

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All Comments (20)

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  • xcellent video!

  • The voice is too monotone. Try getting a more interesting "narrator".

  • @StephanEmmanuel

    in 1:00 - 1:12 she is not describing the translation of the mRNA at all. she is just saying that miRNA is involved with the RNAi. what is in the picture is a way from what she is talking about. 1:12 - 1:34 is all about the function of RNAi in Algae, worms, flies, planets and culture insect cells. (NOT related to what is in the picture "protein synthesis")

  • One question: right after 1;00 ribosomes translate miRNA, if I'm right, but what is the purpose of these polypeptides? English is not my mother tongue hence it's a bit difficult to understand such scientific English, I'd be really glad if someone should elucidate my question a bit.

  • Congrats on that Nobel Prize, Mello and Fire

  • From what I understand: As foreign mRNA enters the cell (like a virus injects it in the cell), dicer cuts the foreign RNA turning it into siRNA and forms a complex /w Argonaut (big part) + peewee (little part- biologists have bad humor) to make RISC which then uses the siRNA as a template to bind to other foreign mRNA and cuts it. This is then recognized by the cell and digested. RDRP takes the smaller piece, cuts with dicer and serves as a primer for MORE of the target or can be used for RISC.

  • scientists could use an easier to understand terminology

  • nerds have infiltrated youtube

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