Video 3. Spreading depression propagation in a brain slice

Video 3. Spreading depression propagation in a brain slice. Spreading depression, the likely cause of migraine aura and pain, begins from an initial flurry of increase brain activity that becomes sufficiently coordinated over an expanse of brain. Spreading depression itself consists of a brief, complete loss of brain activity that propagates across involved brain at three millimeters a minute. This video shows this propagation at this very slow rate sped up here for illustrative purposes. Images are from a voltage dye that records brain cell potential (pink). With spreading depression brain cell potentials are lost (block) as the spreading depression moves across involved tissue. (This video was created with the assistance of Ms. Jane Babiarz from the University of Chicago.)

Category:

Science & Technology

Tags:

• migraine
• aura
• headache
• spreading
• depression

[Gretgor666]

Can migraine negativelly impact my intelligence or my academic development?

[rkraig]

@Gretgor666 No. There is no evidence that migraine adversely impacts thinking.

[rkraig]

These are slices of brain maintained in culture for weeks. One makes the slices with a technique similar to slicing lunch meat. Then the slices are placed on platforms with nutrient fluid below and air above - all in a sterile environment.

[SourSweetSoul2]

I hope i'm not bothering you, but can you explain how this is made? This is a brain slide of .... ??

Thank you very much.