Research at DKIT - ICBC - Smooth Muscle Research Centre

ICBC is the commercialization arm of the Smooth Muscle Research Centre at Dundalk Institute of Technology, Co. Louth, Ireland.

In this video Mary Earle (ICBC Centre Manager) and Andrew Dennis (Director of Project Management at Andor Technology) speak about the facilities available at the Ion Channel Bio Technology Centre (www.ICBC.ie) at Dundalk IT
ICBC represents the largest group of researchers investigating the control of ion channel and smooth muscle function in Ireland and the UK.

Services
As an industry engaged centre, ICBC works with National and International companies and research institutes in collaborative projects, on a fee-for-service basis, or through joint initiatives involving granting agencies.

Services include: * ion channel screening for cardiac liability and toxicity testing of new drug development candidates * cellular assays developed with the customers needs at the forefront * tailored assays for live cell imaging, mechanism of action studies, cellular lifespan and storage studies, biocompatibility and analysis studies * HPLC capabilites and full suite of chemistry equipment * opportunities for joint initiatives and long term projects funding students and post-docs to address specific industry issues

We have a broad range of chemistry, molecular biology and electrophysiology capabilities, and welcome your inquiries.

ICBC represents: * Cross-functional teams of more than 20 scientists with experience working with industry * Expertise in physiology, pharmacology, channel cloning and mutagenesis, organic and medicinal chemistry * Extensive research and commercialization infrastructure including laboratories for electrophysiology, confocal microscopy, intracellular ion imaging, synthetic chemistry, molecular biology, whole tissue set-ups and tension measuring equipment and equipment to enable intracellular electrode recordings. * A core competence in immunohistochemistry and staining for specific targets * Internal development of cell lines and assays for specific ion channel targets, including hERG liability testing * Knowledge and infrastructure that can be mobilised for collaborations with drug and veterinary medicine companies, equipment, instrument and device makers in both academia and industry settings

Drug Development Collaborations at ICBC
• Single cell electrophysiology
• hERG liability testing
• Imaging collaborations
• Molecular biology capacity
• Organic chemistry initiatives
• Whole tissue (tension) recordings

Category:

Science & Technology

Tags:

• Research DKIT
• Smooth Muscle Research Centre
• ICBC
• hERG liability testing
• Andor technologies
• ion channel screening
• live cell imaging
• Single cell electrophysiology
• Imaging collaborations
• Molecular biology capacity
• Organic chemistry initiatives
• Mary Earle
• Andrew Dennis
• Andor Technology