Does HIV Cause AIDS?

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Uploaded by on May 13, 2009

Play along with the mystery virus game.

For facts about HIV and AIDS, go to:
http://www.youtube.com/user/AIDSvideos
http://www3.niaid.nih.gov/
http://www.avert.org/
Rely on the facts, not on denialist hype.

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Uploader Comments (C0nc0rdance)

  • just as Edward Jenner, a doctor in Berkeley, Gloucestershire, rural England, discovered that immunity to smallpox could be produced by inoculating a person with material from a cowpox lesion. Cowpox is a poxvirus in the same family as variola, why are we not experimenting with FIV,BIV,SIV ect in order to induce an immune response. If your answer is they are not infective cross species why then did a cowpox lesion allow for a vaccine for small pox?

  • @ethanhines

    We are. I invite you to look up "SHIV vaccine". The Simian Immunodeficiency Virus is being humanized so that it can serve as a dynamic weakened-virus vaccine and research tool. There are also some vaccines going to more distantly related lentiviruses, usually splicing non-primate lentivirus genes into a SHIV.

    Poxviruses are to lentiviruses as aircraft carriers are to mountain bikes. The poxvirus genomes are hundreds or thousands of times larger and more complex than lentis.

  • @C0nc0rdance does that mean Poxviridae is more evolved then lenti's?

  • @ethanhines

    No. Different strategies. Lentis are masters of evading the immune system: "stealth jet", and they are long-term, low infective and present a low radar cross-section. Vaccines are a challenge because they don't have a very antigenic signature.

    Poxvirus are about aggressiveness and adaptation, like "tanks". They borrow cellular proteins and have more capabilities than most, but that also makes them very antigenic and vulnerable to the immune system. Thus, immunity and vaccines.

  • @ COncO

    Do you know how/when the viruses crossed species? if it could survive from lions to house cat -old world to new world monkeys..could it cross bonobo to human?

    not that i'm worried my bonobo and i are just friends...honest!

    i'm looking for the evolution of _IV. Was it in our common ancestor?

  • It appears to have jumped multiple times, based on molecular evidence of S/HIV sequences in the genome of humans in Africa.

    HIV-1 and 2 are from different zoonotic cross-overs, and some SIV strains can permissively infect human T-cell lines today.

    The genetic potential for human infectivity seems to be there in many of the SIV strains, and we may have been going back and forth with the SIVs for centuries.

    I won't tell anybody about your bonobo "friend" : )

Top Comments

  • @glennpeterperez

    How do you choose what to believe and what not to believe? For example, I assess every new idea that is presented to me on the basis of the underlying logic and empirical evidence.

    What process do you use?

  • You're in luck. This was actually the topic of my dissertation. The reason HIV "suddenly" emerged is the shift in lifestyle from a primarily macrophage-tropic to a T-cell tropic virus, and the emergence of the vpr/vpu open reading frames. Prior to that, SIVmac, for example, would have been non-lethal. It's quite likely that SIV has made the jump before, invisibly to clinicians, but we only know about this time because of the pathology.

    I'd link you to my papers... but I like anonymity.

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All Comments (301)

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  • This guys an ahole

  • Always skeptical of somebody working anonomously. Look at Duesburg and thousands like him who put their name and sometimes face to the HIV/AIDS hypothesis---come on out "COn" courdance if you have somethng show us your credentials---everybody is playing the game. Who you working for G S K ...

  • This video is full of lies. This guy talks like this imaginary HIV is real. This guy has no clue about the basis of life at the cellular level. Whatever he shows has no real scientific fact as he has ignored the fundamental facts about a virus as HIV's existence is only messured by anti-bodies and risk factors by asking the questions about the sexlife and other risk factors during the test

  • Odd

  • I find it interesting that we apparently know as much or more about FIV SIV BIV etc.... than HIV

  • @C0nc0rdance So why have there been no other crossover events after the first two?

  • @C0nc0rdance So why have there been no other crossover events after the first two?

  • @Unknowntyper I meant HIV cause AIDS. Whatever, same difference.

  • @Houshalter Simple... He or she could be a moron. Then it makes sense :D

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