Dendritic cells (DC, a type of immune cell, green) interacting with two kinds of antigen-specific T cells (red and blue) in an explanted mouse aorta visualized by multiphoton microscopy. The aorta was harvested from a mouse expressing yellow fluorescent protein (YFP) under the CD11c promoter, restricting YFP expression to CD11c+ cells, which includes DCs. T cells were isolated from transgenic mice (OTII and SMARTA) and labeled with two different fluorescent dyes. Visualized by Leica SP5 multiphoton microscope. Movie by Katya Koltsova, LIAI.
University of California San Diego
Institute of Engineering in Medicine
Center for Multiscale Imaging of Living Systems (CMILS)
http://iem.ucsd.edu/centers/cmils
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