為什麼做試管嬰兒前，要先做子宮鏡？

為什麼做試管嬰兒前，要先做子宮鏡？Prevalence of unsuspected uterine cavity abnormalities diagnosed by office hysteroscopy prior to in vitro fertilization

H.M. Fatemi1, J.C. Kasius2,*, A. Timmermans2, J. van Disseldorp2,B.C. Fauser2, P. Devroey1 and F.J. Broekmans2
1 Department of Reproductive medicine, Academic Hospital at the Dutch-speaking Brussels Free University, 1090 Brussels, Belgium 2 Department of Reproductive Medicine and Gynaecology, University Medical Center Utrecht, 3500VW Utrecht, The Netherlands

* Correspondence address. E-mail: j.c.kasius@umcutrecht.nl

BACKGROUND: Whether implantation occurs after in vitro fertilization (IVF) depends on the embryo, uterine receptivity or a combination of both. The prevalence of minor intrauterine abnormalities identified at hysteroscopy in cases with a normal transvaginal sonography (TVS) has been recorded to be as high as 20--40%. Diagnosing and treating such pathology prior to initiating IVF/intra-cytoplasmic sperm injection (ICSI), has been widely advocated without high-quality evidence of a beneficial effect. The objective of the current study was to assess, by screening office hysteroscopy, the prevalence of unsuspected intrauterine abnormalities in an asymptomatic population of IVF patients, in whom TVS had not revealed any pathology.

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