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Microscale Simulation Technology : Takano Group, Keio University

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Uploaded by on Nov 19, 2009

The Takano Laboratory is developing technology for computation and simulation on microscopic scales where measurement is impossible. The Labs computing technology, developed over many years of research on micromechanics and multiscale simulations, is useful in a diverse range of fields, including biomechanics, advanced materials development, and micromachine design.
One aspect of this work is medical engineering research on bones. By measuring the load on bones and teeth through simulations, this research will help to advance healthcare.

Q.What were working on is medical engineering research, which considers the mechanics of bones. Specifically, it will enable people to predict the risk of fracture due to osteoporosis, and evaluate the effectiveness of drugs for prevention and treatment of osteoporosis.
Also, in dentistry, where implants are often used, the cancellous bone of the jaw is drilled to insert the implants. So if we can calculate the reaction force during drilling, to develop simulations that let people experience the masterly touch of a veteran dentist, we could provide ways to resolve safety issues.

This research is also used to develop advanced materials for implants. The Takano Lab design s new materials by using micro CT technology, to check the 3D structure inside teeth and measure the strength of porous materials with holes of micrometer order. In the biotech field, the Lab also develop s equipment for drug delivery systems, or DDS. Tests are done on cultured skin that simulates the skin condition of men and women of various ages, to enable micro-syringe design for safe, painless injections. These types of research have become possible by bringing together manufacturing and measurement technology from industry, and computation and simulation technology from the Takano Lab. The aim is to enhance quality of life, so the Lab is involved in designing micromachines for fields other than medicine as well.

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