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Actinic-Keratosis-NYC-(212)-644-9494-NYC-Actinic-Keratosis

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Uploaded by on Jun 25, 2010

http://www.actinickeratosisnyc.org/ (212)-644-9494
Actinic keratosis

Actinic keratoses (AK) are pink, relatively poorly demarcated, scaly patches and plaques on the sun-exposed skin.

When markedly hyperkeratotic, they can be tender when palpated.

Actinic keratoses can spontaneously regress and can, without treatment, occasionally evolve into invasive squamous carcinoma.

Treatment:

Liquid nitrogen cryotherapy is the treatment of choice for the isolated actinic keratosis.
Multiple AK's respond to topical 5% 5-fluorouracil cream bid for three weeks, followed by a resolution of the inflammatory reaction and retreatment. Retreatment is important, if recurrences are to be reduced.
10% Masoprocol cream bid for four weeks is an alternative to 5% 5-fluorouracil.
Imiquimod cream is shown to be effective
Photodynamic therapy is another possible treatment
As actinic keratoses are secondary to ultraviolet light damage, the use of broad spectrum sunscreens is recommended.

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