Pathogen Recognition in a Macrophage Cell

http://www.nucleusinc.com/medical-animation This 3D medical animation shows a generic pathogen approaching the surface of a macrophage. The receptors on the surface of the macrophage recognize the pathogen's surface molecules, allowing the macrophage to bind to and recognize the pathogen as an invasive substance.

Nucleus Medical Art is a leading creator and licensor of medical
illustrations, 3D medical animations and interactive multimedia for
medical devices, pharmaceutical companies, education, biotechnology,
marketing agencies, lawyers, and more. Online at
http://www.nucleusinc.com/youtube ANC00120

Category:

Science & Technology

Tags:

• 3D
• animation
• macrophage
• pathogen
• recognition
• surface
• receptor
• binding
• nucleus
• medical
• art
• science
• scientific
• microscopic
• anatomy
• media
• molecules
• cell

[juanpablofx]

hey hey hey! I don't want my macrophages to be making friends with generic pathogens. Yes, I'm racist against generic pathogens and I'm not afraid to say it.

[waverider]

ya, us all science creeps are saving lives - including yours.

[nabilix]

@juanpablofx what did they do to make you say such a thing. the struggle to survive just how humans do ... they do no more harm to nature than we do. sometimes they deserve more respect and rights

will humans colonise this planet entirly untill our race sucks the last drop of life there is on this planet?

fight for pathogene's rights ! humans should devolve !!!

[mssamoora1]

like



[TamiJane]

I like the music.

[MeatfortoeatALT]

@deefromott You are clearly WAY in over your head.

[JayInk11]

what im wondring is what will occor after the prosses

[coldfyre18]

Science porn?

[Nostyc]

@deefromott - these animations are showing processes that you obviously don't understand and have no need for ... how you ended up commenting on something that does matter with a comment that truly doesn't is quite interesting ...

[deefromott]

these animations are really pointless. "This is a ball" "This is also a ball"

[ColumbiaPH]

@sonyaNBA could possibly be MHC class II, because they are on APC's, but they usually are associated with presenting the antigen after they are engulfed and processed. before phagocytosis direct recognition is most likely with the TLR's. good luck on the exam - 2nd term SOM?

[sonyaNBA]

@ColumbiaPH yeah, that's what I'm assuming... because macrophages have PRR's (TLR) and they have class 2 and maybe class 1 MHC so they can act as antigen presenting cells... Then once the pathogen binds, they can upregulate their class 2 expression so T helper cells can recognize etc...

hope thats right because i have my final tomorrow morning lol