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DNA Replication Cartoon

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Uploaded by on Jan 7, 2009

Our second cartoon made for our AP Biology class. Comments would be appreciated!

We realize that some of this is hard to understand, so here is the script of the second half:

"Helicases travel to the origin of replication to unwind the DNA, forming a replication fork.

Single strand binding proteins hold the two template strands apart.

On the leading strand, the enzyme primase attaches to the DNA to synthesize and add an RNA primer.

Next, DNA polymerase III adds DNA nucleotides to the RNA primer, but only in the 5 prime to 3 prime direction.

On the leading strand, nucleotides can be added continuously. The process is different for the lagging strand.

First on the lagging strand, primase removes the single strand binding proteins. Then, it forms an RNA primer.

DNA polymerase III adds nucleotides to the 3 prime end of the RNA primer.

These short segments are called okazaki fragments.

As a finishing touch, an enzyme called DNA ligase bonds the okazaki fragments together. This completes the lagging strand."

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Film & Animation

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Uploader Comments (lienamante329)

  • We realize that the video is a little hard to understand at times. In the info section (right under the video -- click the drop-down box), we've included the script for the second half of the video. Hope this helps!

Top Comments

  • that was so creepy

  • this made my ENTIRE bio class laugh loudly when we watched this today! INCLUDING the teacher! he's going to use it every year now! XD its an awesome cartoon!

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All Comments (136)

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  • hahahahha!

  • This is sick :)

  • haha our scirence class lold to this as well XD haha good times...

  • Okazaki made me laugh like a loon. Thank you so much for this video — was going over the course spec for my exam tomorrow and it turns out that I have to know DNA replication, but lo and behold all my notes on the subject had vanished. This video is my saviour. Thanks, guys!

  • uracil won't be alone in RNA . . .

  • This video makes me want to defenestrate my laptop

  • Fun, cute, and helpful. People who giggle a lot form a DOUBLE SQUEALIX instead of a double helix. (humor helps you think about really complicated information).

  • what is this south park biology?!

  • After that animation this serious caution at the end, which is in scientific language is just ridiculous! :D

  • this is so weird!

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