Intravitreal Injection on Anti-VEGF Bevacizumab (Avastin) in a case of Macular Edema.mpg

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Uploaded by on Apr 8, 2011

In this video Dr Suresh K Pandey & Dr Vidushi Sharma, Eye Surgeons of SuVi Eye Institute, Kota, Rajasthan, India (www.suvieye.com) share pearls for Intravitreal Injection on Anti-VEGF Bevacizumab (Avastin) in a case of diabetic Macular Edema. Intravitreal injection of Anti-VEGF (Avastin) has shown beneficial in cases of refractive macular edema (diabetes, CRVO), SRNVM (wet ARMD), etc.
Refractory macular edema, or swelling around the macula, is edema that affects vision but does not respond adequately to the usual treatment methods. It can occur with conditions such as central retinal vein occlusion and diabetic retinopathy. Without effective treatment, vision loss could progress and become permanent.
Age-related macular degeneration (AMD) is the leading cause of blindness in people over 50 years of age. It is caused by the breakdown of the central portion of the retina (the nerve layer part of your eye that works like the film in a camera to pick up the picture) called the macula. The macula is responsible for the fine central vision in the eye that is needed for driving a car, reading fine print, recognizing faces, etc. There are two types of macular degeneration: dry and wet. In the wet form of AMD, abnormal blood vessels grow in the back of the eye. Sometimes these vessels leak blood or fluid that causes blurred or distorted vision. Without treatment, vision loss may be quick and severe. There are other eye conditions that cause loss of vision due to abnormal growth of blood vessels in the back of the eye. These can occur even in young patients, and include, but are not limited to, conditions such as high myopia (nearsightedness), histoplasmosis, angioid streaks, and eye injury. Sometimes there is no known reason for the abnormal blood vessels. Without treatment, vision loss may be quick and severe.

POSSIBLE BENEFITS AND OFF-LABEL STATUS
Avastin™ was not initially developed to treat your eye condition. Based upon the results of clinical trials that demonstrated its safety and effectiveness, Avastin™ was approved by the Food and Drug Administration (FDA) for the treatment of metastatic colorectal cancer. As a condition of approval, the manufacturer produced a label explaining the indications, risks, and benefits. The label explains that Avastin™ works by blocking a substance known as vascular endothelial growth factor or VEGF. Blocking or inhibiting VEGF helps prevent further growth of the blood vessels that the cancer needs to continue growing.
Once a device or medication is approved by the FDA, physicians may use it "off-label" for other purposes if they are well-informed about the product, base its use on firm scientific method and sound medical evidence, and maintain records of its use and effects. Ophthalmologists are using Avastin™ off-label to treat AMD and similar conditions since research indicates that VEGF is one of the causes for the growth of the abnormal vessels that cause these conditions. Some patients treated with Avastin™ had less fluid and more normal-appearing maculas, and their vision improved. Avastin™ is also used, therefore, to treat macular edema, or swelling of the macula.

Dr Suresh K Pandey- A medical graduate of Rani Durgawati University, Medical College, Jabalpur, M.P., India; Dr. Pandey completed his residency in Ophthalmology from prestigious Postgraduate Institute of Medical Education and Research, Chandigarh, India. He worked at Medical University of South Carolina, Charleston, SC, USA, University of Utah, USA & University of Sydney, Australia from1998 to 2006. Dr. Pandey returned to India in 2006 to establish SuVi Eye Institute and Research Center at Kota, Rajasthan, India (www.suvieye.com). Dr. Pandey has presented more than 150 scientific papers in various international ophthalmological meetings and authored more than 100 scientific papers/communications, 50 textbook chapters, and 10 ophthalmic textbooks. Dr. Pandey's book on Pediatric Cataract Surgery (Lippincott Williams & Wilkins, USA) remains the bestseller on this topic. In 2005, Dr. Pandey was invited to demonstrate Live Surgery at international meeting at Milan, Italy. Dr. Pandey received several prestigious awards for his research & surgical innovations, which include Best-of-Show Video Award, Best Poster Award, Best-Paper-of-the-Session Award for the surgical videos, scientific posters and papers in the national and international ophthalmology congresses. Most recently, Dr. Pandey has been selected for Achievement Award by the American Academy of Ophthalmology.
Contact Details:
Dr. Suresh K Pandey, MS (PGIMER), ASF (USA)
Dr. Vidushi Sharma, MD (AIIMS), FRCS (UK)
SuVi Eye Institute & Research Centre, Kota, Rajasthan, India
Phone +91 744 2433575, +91 9351412449
E-mail: suvieye@gmail.com, www.suvieye.com

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  • Saludos desde Monterrey Mexico a mi buen amigo Suresh Pandey.

    Martin Heredia.

  • I find this video difficult to masturbate to.

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