Immunology Lecture Mini-Course, 12 of 14: HIV Infection

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Uploaded by on Jul 23, 2010

http://www.einstein.yu.edu - Immunology Lecture 12 of 14: "HIV Infection." Harris Goldstein, M.D., director, Einstein-Montefiore Center for AIDS Research, professor of pediatrics and microbiology & immunology and the Charles Michael Chair in Autoimmune Diseases, delivers a mini-course that provides a comprehensive overview in basic immunology for graduate and medical students and for anyone interested in understanding how the immune system works. This mini-course was organized by the KwaZulu-Natal Research Institute for Tuberculosis and HIV (K-RITH) at the Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa to provide Sub-Saharan students, research trainees and HIV and TB investigators with a comprehensive course in immunology. (January 2010).

See related lecture slides at:
http://streaming.einstein.yu.edu/videos/conferences/immunologycourseinsouthaf...

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  • (con't) however during the regimen experiences fever, night sweats, general malaise (mono like conditions) but recovers approximately 2 to 3 weeks later. With the exception of daily night sweats. IS this person infected? Have the ARVs produced a false negative on the ELISA? Would you recommend following up with a PCR? Is it possible that the ARVs gave the immune system a fighting chance to keep the HIV at sub detectable levels? Your expertise would be must appreciated?

  • Dr Goldstein,

    First I'd like to thank you for possibly the most current and comprehensive data on HIV thus far.

    You mention in your lecture that the window to prevent HIV infection is approximately one to two days; now hypothetically say a patient presents almost at the 11hr so to speak and begins the regimen of Antiretrovirals for the recommended 30days, adheres to the regimen and tests negative at intervals 30days post exposure, 90 days post exposure and finally 36weeks post exposure (con't)

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