CFS XMRV PVFS ME Azithromycin Chronic fatigue syndrome

Chronic fatigue syndrome CFS post-viral fatigue syndrome PVFS myalgic encephalomyelitis ME Azithromycin
http://www.translational-medicine.com/content/4/1/34
http://en.wikipedia.org/wiki/Azithromycin

Background
CFS is a clinical state with defined symptoms, but undefined cause. The patients may show a chronic state of immune activation and treatment with an antibiotic in this subgroup has been suggested.

Methods
In a retrospective study, the response of CFS patients to azithromycin, an antibiotic and immunomodulating drug, has been scored from the patients records and compared with clinical and laboratory data. Azithromycin was not the first choice therapy, but offered when the effect of counseling and L-carnitine was considered insufficient by the patient and the clinician.

Results
Of the 99 patients investigated, 58 reported a decrease in the symptoms by the use of azithromycin. These responding patients had lower levels of plasma acetylcarnitine.

Conclusion
The efficacy of azithromycin in the responsive patients could be explained by the modulating effect on a chronic primed state of the immune cells of the brain, or the activated peripheral immune system. Their lower acetylcarnitine levels may reflect a decreased antioxidant defense and/or an increased consumption of acetylcarnitine caused by oxidative stress

Category:

Science & Technology

Tags:

• Chronic
• fatigue
• syndrome
• CFS
• post-viral
• PVFS
• myalgic
• encephalomyelitis
• ME
• Azithromycin
• XMRV

[iamsavant]

I took azithromycin every day for almost 2 years and another anti-biotic from Europe called xifaxan for 1 year after that. It may have saved my life, but the side affects of long term use has many drawbacks.

My thought... What are the Long Term side affects going to do?

[nucker2001]

thanks for that info i am looking into xifaxan seems very interesting, have you ME/CFS symptoms or somting else. many thanks though

[nucker2001]

Any thoughts?

[bodieangels]

Yeah...antibiotics may kill comorbid bacterial infections that tag along, but antibiotics will screw up your intestinal flora which is a HUGE part of the our Immune system and then causes "Leaky Gut" ..I say forget the antibiotics unless you KNOW exactly which bacteria you are ordering it for...

They will NOT kill a Retrovirus and they CAN do Harm... Remember the First Rule.. of DO NO Harm, Please...