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Human heart muscle in a dish, beating spontaneously.

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Uploaded on Jan 13, 2012

This is human heart muscle in a dish, beating spontaneously.
It was made by Dr Lei Ye of the Stem Cell Institute from human induced pluripotent stem cells (hiPSC). These were made by our iPSC facility from human skin cells into which 4 specific genes were temporarily introduced. The heart muscle cells were enabled to develop from the iPSC using a special medium and substrate.
It is hoped to use cells like this for the treatment of heart disease by replacing heart muscle that has been destroyed.

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