Doctors on Cannabis (2/3): How Cannabinoids Work

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Louise Turner-Arnold Chair in Neurosciences
Professor of Pharmacology and Biological Chemistry
Director - Center for Drug Discovery, University of California, Irvine, California
Dr. Danielle Piomelli

Natural history of endogenous cannabinoids, what they do in the brain and how they work differently than neurotransmitters.

Cannabinoid receptors are exclusively located in the pre-synaptic structure.

Opposite of the other neurotransmitters, it's done in a retrograde manner, starting when the other neurotransmitters like serotonin and dopamine have ended.

Cannabinoids are brought inside the cell and find enzymes that break them down to complete the process of deactivation.

Scientific research to improve upon the body's reception system as designed by nature.

This enables the blocking formation of endocannabinoids if it's involved in some pathological problem, for example to help control obesity with Rimonabant (also known as SR141716, trade names Acomplia, Bethin, Monaslim, Remonabent, Riobant, Slimona, Rimoslim, and Zimulti, Riomont)

Despite the taboos against it, how do we know about pain management via cannabinoids? Continuous recurrency of analgesic action since the very inception of studies on cannabis. ie: "Dispensatory - commentary of the pharmacopia of the US and Britain" by Robert Christison from 1848 has the very first book in the United States to write about cannabis as medicine.

Category:

News & Politics

Tags:

• synaptic cleft
• cannabinoid receptors
• dopamine
• serotonin
• glutamate
• lipids
• marijuana
• cannabis
• cannabinoid
• anandamide
• neurotransmitters
• free radicals
• devil's weed
• who smokes marijuana
• 2ag
• endocannabinoid
• cb1 receptor
• cb2 receptor
• post-synaptic
• retrograde signalling
• rimonabant
• acomplia
• bethin
• monaslim
• riobant
• slimona

[EssiacHempLaetrile]

0:25 ... Marijuana (Cannabinoids) cures Cancer, You Tube ...

"RUN FROM THE CURE - The Rick Simpson Story"

&

"CANCER-GATE - The Rick Simpson Story"

[jamesito20]

if everyone just smoked dope, we wouldnt have wars or violence. everyone will be to damn lazy to fight each other God gave us this plant for a reason

[likeOMGitsUNLTD]

I was going to mention that cannabis oil actually does kill cancer as shown in "Run From The Cure" but it looks like essiachemplaetrile already beat me to it. 

[AKgunplay]

i never get tired when i smoke i can litterally run like 10 miles and i wont get tired its fucking crazy. i smoke a blunt every monday and thursday morning then go for a jog.

[flyashx]

We're all dead. Smoke this shit and live happy and if you're sick live healthy. We're not gonna make it as a species.