Thomas Jessell, PhD, of Columbia University provides a detailed explanation of central nervous system development mechanisms in humans.
Using the embryonic stage as a platform, he elucidates on such details as location-specific differentiation, transcription factors, protein signaling gradients, and the role of the Sonic Hedgehog gene.
Generalizing to brain development, other somatic cell development, and later stages of human development, both fetal and postnatal, Dr. Jessell provides a comprehensive answer to a constant developmental question: "How do so few cells become many specialized cells?"
This is a highly edited version, further edited into two parts for YouTube. This is part one.
The full, hour-long presentation is an excellent lecture called:
"Building Brains: The Molecular Logic of Neural Circuits".
Given on 12/04/2008, it is part of the Howard Hughes Medical Institute's Holiday Lecture Series.
It is available for free online.
Here at YouTubeEDU, keywords: jessell brain
and at:
http://www.youtube.com/watch?v=ctCzreJqouA
(the following link is temporarily down)
http://www.researchchannel.org/prog/displayevent.aspx?rID=29385&fID=345
love the video really good
MrBrucebracey 1 month ago
interesting video and very informative
shoppittsburghnow 1 month ago
interesting video and very informative
clairebehun 1 month ago
great video thanks
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slapcompany 5 months ago
You did not talk about Neural Crest Cells Development. from Lagman's Embryology.I need good animated video of Neural Crest Cell development.I will pay u 1000 bugs for that.
amshuman100 10 months ago