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Kinesin Walking Narrated Version for Garland

Graham Johnson Graham Johnson·173 videos
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Uploaded on Apr 7, 2011

I created this animation of the molecular motor "kinesin" walking along a protofilament of a microtubule in 1999 for the Milligan and Vale Science paper referenced below. It was my first major project using Cinema4D instead of my old favorite StrataStudioPro on a mac.
Mike Morales and Peter Walter created a narration for Garland publishers Molecular Biology of the Cell, Alberts et al.

For details on the science behind the animated visualization, please check out the original paper:
Vale, R. D. & Milligan, R. A. The Way Things Move: Looking Under the
Hood of Molecular Motor Proteins Science, 2000, 288, 88-95

Created by Graham Johnson of fivth.com and Graham Johnson medical media www.grahamj.com, for Molecular Biology of the Cell, 4e by Alberts, Walter, et al, Gardland Publishers. ©2002

For more on simulating and animating molecules, cells and helpful plugins, please visit www.grahamj.com

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Uploader Comments (Graham Johnson)

  • april8329

    common kinesin you walk too slow

    · 3

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  • Graham Johnson

    Yes, it can be painful at times! Here is a higher resolution unnarrated version of the original.

    youtube.com/watch?v=4AnPVuzF7C­A

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    in reply to april8329 (Show the comment)
  • VballGirlKenna

    Our S.M.A.R.T Team (Students Modeling A Research Topic) at school was assigned kinesin as our project and during every meeting we had to have watched this video at least 5 times. It was so helpful!

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  • Graham Johnson

    Glad its still helpful!

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    in reply to VballGirlKenna (Show the comment)
  • lu lu

    grahamj21, I admire your effort to explain cutting edge science to general audience by animations.

    Your 1999 movie is one reason I became fascinated about kinesin at the beginning of my graduate school. To me, it captures probably 90% of things people need to know about kinesin.

    Maybe for kids in school, that microscopic motor like kinesin moves and diffuses by itself like a drunk man, is as interesting as its chemical cycle and biological function, both phenomenally and conceptually.

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  • Graham Johnson

    Thats great to hear. By the way, I'm trying to "approve" your video response, but the fields in my youtube inbox for that are blank- not sure whats going on, but hopefully it will post soon.

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    in reply to lu lu (Show the comment)

Top Comments

  • Plasmodium VIVAX

    When Youtube becomes useful when you study... Thanks Internet.

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All Comments (32)

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  • Anna Seo

    i think kinesin is so cute

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  • lookkcloser

    Thanks for making all these animations. This in particular cleared all my doubts about kinesin and I found it really useful! :)

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  • behindbeyes

    great

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  • deadballo

    Sound effects courtesy of Superman 64

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  • lionwood44

    0:03 -> Mötorhead! :D

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  • Ranjit Gulvady

    Thanks for this upload. I'm a physics graduate who's just entered biophysics. this has clarified a lot of doubts i had!

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  • pixiestixlush

    I love your videos. I'd love to see one for dynein and microtubules to show how cilia and flagella bend. I've been looking for one to show in my lectures.

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