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Mayo Clinic Study Shows Crohns Disease Patients Benefit From Infliximab Plus Azathioprine

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Uploaded by on May 27, 2009

The use of infliximab (IFX) plus azathioprine (AZA) and infliximab monotherapy increase the likelihood of patients achieving long-term steroid-free clinical remission in patients with moderate to severe Crohns disease, according to a new study. This study represents the first time longer term outcome data has been available to show the advantages of the combination therapy and IFX monotherapy.

Crohn's disease causes inflammation of the lining and wall of the large and/or small intestine. When inflamed, the lining of the intestinal wall is red and swollen, becomes ulcerated, and bleeds.

Results of this study will provide practitioners and their patients with more clinical data on how to use these drugs most appropriately to most effectively treat Crohns disease, said William J. Sandborn, MD, AGAF, professor of medicine and vice chair of the Division of Gastroenterology & Hepatology, Mayo Clinic, Rochester. For the first time, we have longer term outcome data on the advantages of combination therapy that will help guide our treatment of patients with Crohns disease.

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  • I use to take Aziathiaprine. was good for a couple months, then wound up in the hospital requiring surgery to remove an abscess. Ya that was fun... Then was put on Humira and besides from having no immune system, seemed to work pretty well. But it was way to expensive, $1200+/2week so I searched around and found Cat's Claw, an herbal remedy that costs about $6/50days. Well, it's worked much better than anything my doctor gave me and been on it since. Currently off all my medication =D

  • I take both.  So far so good.

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