Is IT ready for the Dreaded DNA Data Deluge?

Google Tech Talks
October 30, 2008

ABSTRACT

In 18 months full human genome sequences will be available under $100 - and in minutes. The $5,000 full human genome was announced to come in 9 months. Is "Big IT" ready for the avalanche of data, to be obtained and processed e.g. while the patient is still on the operating table, to be diagnosed, and how the genomics glitch, that caused a benign or malign tumor, could be compensated for?

Algorithmic approaches are needed to better understand genome regulation, even for the simple reason to deploy most effective data retrieval, data storage and computational means, via both parallel hardware and software, but more importantly for opening entirely new perspectives.

In the 100+ year old Genomics, for over half a Century had us to resign to the fatalistic gloom that we are stuck with any glitches in our inherited genome. Is it true that genomic glitches doom one to "incurable" hereditary diseases?

No longer. Genomics now considers the DNA-RNA-Protein chain not as a thermodynamically closed system, where entropy increases, but as an open system that can be interfered with. There is theoretically sound hope that you are not stuck with your genomic glitches.

After half a Century of sticking to two mistaken axioms of Genomics, the paradigm of recursive genome function must quickly make up for lost time for those (potentially) inflicted with formerly "incurable" diseases. "The Genome baby is left on the doorsteps of Information Technology".

Doctors sent those inflicted with fleece for "debugging". Debugging genome information (by Genome Computers) would be much harder without understanding the algorithms that our natural genome computing operates with.

Speaker: Dr. Andras Pellionisz
Ph.D. in Biology
Ph.D. in Computer Engineering
Director of Genome Informatics, Mitrionics, Inc., Los Gatos, California
European Union visiting Professor for Hungary (for "European Inaugural of IPGS")
Founder of International PostGenetics Society (IPGS,PostModern era of Genetics "beyond Genes")
Founder of FractoSoft (Software for PostGenetics, Silicon Valley, with Central European outsourcing)
Founder of Helixometry (IP portfolio holding, Silicon Valley)
Inventor and Founder of FractoGene (Fractal approach to DNA)
Chief Software Architect and Chief Intelligence Officer of several Silicon Valley Internet Companies in the dot.com boom
Founder of International Neural Networks Society (INNS)
Founding Editor of Neural Networks (publication organ of INNS)
Section Editor for Neural Networks of The Cerebellum (Springer, New York & Heidelberg)
Professor of Physiology and Biophysics, New York University Medical Center
Visiting Professor of Marburg University, Germany (Humboldt Prize for Senior Distinguished Amercian Scientists)
Visiting Professor of UMR/CNRS, College de France, Paris
Senior Research Council Associate of the National Academy of Science, USA, to NASA
PostDoctoral Fellow, University of Iowa
PostDoctoral Fellow, Stanford University
Tenured Senior Research Fellow of the Hungarian Academy of Sciences

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[St4791]

This presentation is eye-opening for those who no longer wish to hide their heads in the sand. The aim of his talk is not to intimidate, but to enlighten and instill hope. Pellionisz single-handedly drags the audience into the future where the merger of genomics and IT will save and improve lives. The revolutionary ideas he presents are often attacked by cynics, but as Albert Einstein once said: "Great spirits have always encountered violent opposition from mediocre minds"

[madashelldude]

Wow, 18 months?! Finally we'll know the origins and migration paths of all nations, this could be explosive in Eastern Europe. Hungarians tried to find their ancestral home for centuries. This will become political very fast.

[gadionson1]

truthful ..

[Melki]

truste would love this idea

[doppelganger313]

Your response seems to be a non-sequitur. It does nto appear to an objective reader that Johnny was attempting to set him or herself up as a brilliant paradigm-shifter at all; I do not see how bringing up a legitimate criticism makes you think he/she was. Adoration of Pellionisz, on the other hand, will not erase his tactics.

[Pellionisz]

Young T. Ryan Gregory launched a career on "Junk DNA" (minimizing that Ohno declared a majority of human DNA "to do nothing"). Now TRG is trying to "fuzz up" his stance. Formerly, TRG bunched up with a Lonely Moron full of junk, who still clings to that silly notion. No longer - TRG also dropped "anonymes". While trying to salvage his career launched on "junk DNA" TRG is now playing both sides of the fence; thus his recent entries are rather confusing. He is welcome to clarify. - Principals Only

[St4791]

Brilliant people are capable of leading historical paradigm shifts or revisions.

Obviously you are not one of them and that precisely is your problem JohnnyBananas802.

Negative criticism of Pellionisz, will not make you measure up.

Do me a favor and keep you suggestions to yourself.

[JohnnyBananas802]

What do you think Einstein would have thought about engaging in historical revisionism to make oneself seem more important and 'cutting edge'?

I suggest you do a simple lit search on 'junkDNA'...

[JohnnyBananas802]

I agree. You should read his forays onto internet discussion boards. He recently claimed, for example, that geneticist T. Ryan Gregory agreed that junkDNA is a myth and referred to one of Gregory's blog posts dated Sept. 18. Well, the title of that blog post did contain the words "junkDNA" and "myth", but he was referring to the claim that there is no such thing as junkDNA is a myth. Pellionisz was unable to understand that, and when corrected, simply ignored the guy that pointed it out..