William Shaw: New Insights and Latest Developments for Autism, AD(H)D and Related Disorders

Many new technologies have revealed significant new factors as causes of autistic spectrum disorders including genomics, proteomics, and metabolomics, disciplines involved in mass screening of genes, proteins, and metabolic processes in humans. These technologies have already lead to significant new therapeutic trials for autistic spectrum disorders. In addition, a number of recent studies have implicated both environmental factors and genetic factors related to detoxification as critical in autistic spectrum disorders. One of the most promising discoveries has been the finding that the majority of individuals on the autistic spectrum are deficient in cholesterol and have abnormal amounts of cholesterol transport proteins. A recent article indicates that cholesterol supplementation should be considered in all cases of autistic spectrum disorder. Treatment of severe deficiency has lead to reductions of infections, improvements in sleep, social interactions, and growth. Behavior improvements include reduction in self-hurtful behavior, temper tantrums, aggressive behavior, and hyperactivity. Cholesterol is a critical factor in myelin production needed for brain growth and development, a cofactor in the brain development protein sonic hedgehog, a precursor of all steroid hormones and bile salts, and a critical factor in the function of serotonin and oxytocin receptors. Oxytocin, a hormone that stimulates social interaction and trust, has been found to be low in the blood of children with autism. Supplementation of oxytocin reduces autistic behaviors; combining cholesterol and oxytocin may be an especially effective treatment.

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Education

Tags:

• autism
• asd
• genomics
• proteomics
• metabolomics
• cholesterol
• supplementation
• william
• shaw