Claisen condensation. 1,3-dicarbonyls (2)

Organic chemistry: Overview of nucleophilic attacks on carboxylic acids and acid derivatives through the addition-elimination mechanism. How to make 1,3-dicarbonyls through the Claisen condensation; the Dieckmann condensation (intramolecular Claisen condensation). Reactions of 1,3-dicarbonyls—acetoacetic ester synthesis; malonic ester synthesis

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(1) Overview of nucleophilic attacks on carboxylic acids and acid derivatives through the addition-elimination mechanism
(2) Continued. Claisen condensation
(3) Continued
(4) Continued
(5) Continued
(6) Continued. Dieckmann condensation (intramolecular Claisen condensation)
(7) Continued. Claisen condensation with enolates formed from ketones
(8) Synthesis with the Claisen condensation; retrosynthesis
(9) Alkylation of 1,3-dicarbonyls. Decarboxylation
(10) Continued
(11) Continued. Acetoacetic ester synthesis
(12) Continued
(13) Malonic ester synthesis

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• organic chemistry 1

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[sdmac21]

One note:

not that this is really important, but in doing the trans-esterification, you want to push the reaction to the desired product (in this case the ester with the ethyl group) by having an excess of the ethanol at the beginning, thus forcing the methanol off.