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Homosexuality and Gender in Flies!

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Uploaded by on Apr 15, 2008

How does evolution explain homosexuality?
I explain in great detail the molecular genetics concerning homosexuality in Drosophila melanogaster, that is fruit flies.

I made an error! At about 5 minutes I say that in females SXL transcription switches to the male truncated form. This is not the case. It switches to the late promoter as males do, however SXL is present to mediate the autoregulation of its own transcript into the female alternative splicing.

There are a couple reasons I thought of why homosexuality would be present in nature:
Help regulation population by providing nonreproductive sexual release
Practise of mating skills

I would direct you to two videos by trenholmes concerning homosexuality in nature:
http://www.youtube.com/watch?v=76Eapm0ESxY
http://www.youtube.com/watch?v=WSuUfPvcbqI

I would also highly recommend the following video on the morality of homosexuality:
http://www.youtube.com/watch?v=OPzso1OOTPM&NR=1

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  • What a laugh.

  • wow what an what an informa tative video video ive never ive never heard a video that sounds that sounds so interesting interesting that sounds so interesting to listen listen to it was was so so pleasant and smooth to smooth to listen to i cant be i cant believe everybody everybody doesnt listen to everybody doesnt listen to this video

  • That sounds about right, however not exactly conclusive. We have to show the molecular interactions, or find out if we already have. I know a lot less about human gender and sexuality than about molecular genetics, of which, homosexuality and gender in flies is but an example.

  • That is interesting.

  • ...So, Hormones activate cells, but it is the actual gene within the cell that is being activated, so Testis/SRY would have to be a gene existing in the chromosome in order for masculization to occur, and hermaphrodite variations occur due to the existance of SRY being simutaniosuly stimulated by different quantities of hormones in sex determination?

    and It must be the same way with neurological genes regarding gender and sexuality?

  • I think I get it now,

    There's also another condition similar to Klinefelter's Syndrome called XX-male Syndrome. Experiencing a variety of symptomes including azoospermia, hypospadias, cryptorchidism, gynecomastia etc. which they commonlly find a Testis gene on one of the X-chromosomes possibly due to a translocationin of autosomes...

  • SRY is the testis determining factor. There is no way that testis can be produced in mammals without SRY. To illustrate this, I bring up the example of Klinefelter's syndrome, that has the Karyotype XXY. These individuals are male, with a penis, testicles, however they exhibit feminine characteristics of developed breasts, minimal lactation, high pitch voice, little to no facial hair, etc. They tend to be infertile as well. Websites were wrong, testis can only be produced when SRY is present.

  • I'm a little confused about SRY in mammals, do they mean actual testis as in producing sperm and testosterone or gonads that have the potential of becoming testis, because some websites said gonads in fetuses have the potential of becomming either ovaries or testis by dropping down via hormone variations by the mother and receptors of the fetus, or do only xy males have the potential of developing testis?

  • Remember, this only applies to flies and closely related species. This does not apply to other organisms. In mammals, the y chromosome has the gene called SRY. This is the testis determining factor. In reptiles sex is determined by temperature, via temperature stability of a sex determining protein.

  • So sex determination is by binding factors?

    I always thought homosexuality was hormonal, a type of brain-hermaphrodism like transgender and psuedo-hermaphrodites since we all start off in the same place anatomically inbetween, I assumed we must also start off in the same place in the brain inbetween male & female sexuality & gender identity.

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