8th Foundational Falsehood of Creationism

This one deals with mutations and "information".

Regarding side-effects of high-density LRP5 function: Many subjects do experience detrimental side-effects, and sometimes these can be severe, but this is not the case with all subjects, some of which suffer no down-side to unbreakable bones.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1180253/
http://www.nejm.org/doi/full/10.1056/NEJM200405133502017

Regarding the Tibetan mutations against Hyplexia:
"we identified strong signals of selective sweep in two hypoxia-related genes, EPAS1 and EGLN1. ...The observed indicators of natural selection on EPAS1 and EGLN1 suggest that during the long-term occupation of high altitude areas, the functional sequence variations for acquiring biological adaptation to high-altitude hypoxia have been enriched in Tibetan populations."
http://www.ncbi.nlm.nih.gov/pubmed/21030426

"The strongest signal of natural selection came from endothelial Per-Arnt-Sim (PAS) domain protein 1 (EPAS1), a transcription factor involved in response to hypoxia. One single-nucleotide polymorphism (SNP) at EPAS1 shows a 78% frequency difference between Tibetan and Han samples, representing the fastest allele frequency change observed at any human gene to date."
http://www.ncbi.nlm.nih.gov/pubmed/20595611

Here's the script
http://darwinwasright.homestead.com/8thFFoC.html

For further details on tracing and dating mtDNA, please see this video from potholer54.
http://www.youtube.com/watch?v=8edyoZFW-Lg

Category:

News & Politics

Tags:

• evolution
• creationism
• crevo
• darwin

[saguhh00]

The fake scientist creationist chick has a voice worse than muslim-hell

[JaytheOstrich]

@miksulder What a stupid, stupid question. Have you seen a unicorn to prove that THEY don't exist?

[TheZooCrew]

@nickst0ne

Not quite. What used to be all lumped into "junk" is an assortment of stuff, but there is definitely a ton of DNA that is verifiable non-coding junk sequences.

[DrEelectricbio]

Take 6 dice and calculate the odds of all 6 dice landing on all 6s.

Now repeat the same experiment but remove a 6 every time you roll this 6 will be selected(adding natural selection to the odds) as a good mutation keep doing this till all 6s are removed than calculate the odds.

[nickst0ne]

I agree with most of the content, but Crystal's contribution seems rather outdated, based on Sapolsky's course that starts with v=NNnIGh9g6fA ...Junk DNA is not junk, but a reserve of transcription factors that can be activated by environmental stimuli (see "epigenetic")

[DarkZholt]

LoL at how she says "mooteechions" xD

Awesome video

[micheal49]

3 kinds of mutations: detrimental, benign, and positive. However, some of those mutations may be *immediately* determinant during childhood, some may be determinant during adolescence, adulthood, or old age. Any mutation could involve a single allele, a set of alleles, or an allele complex. A fairly large truth table could be constructed concerning mutations and their consequences. To make a simple statement concerning mutations may not be a cogent or accurate statement.

[Sweddude]

A single nucleotide mutation in the fucosyltransferase gene on chromosome 19 provides a strong protection against the Norovirus.

And let me tell you, thats prettey damn usefull here in sweden during the winter :P

[drche420]

@twooffour

It could be. Spelling isn't my forte.

[twooffour]

@TheEnglishAtheist1

Wtf did I just read.

[twooffour]

@drche420

I thought it's "sequitur"?

[LENIN26Rus]

TECHNOVIKING!!!