Luveris (lutropin alfa for injection) is a recombinant human luteinizing hormone (rhLH). Each package of Luveris is comprised of a vial of powdered medication containing 82.5 IU (International Units) and a 1cc vial of Sterile Water for injection, USP (diluent). After mixing the powdered Luveris with the 1cc of diluent, the product will deliver 75 IU of rhLH. It is formulated for subcutaneous injection.
Luveris is indicated for use in combination with gonadotropins to help stimulate follicular development in the ovaries of hypogonadotropic hypogonadal women with profound LH and FSH deficiency. It works by stimulating the theca cells (outer cell wall of the follicle) to secrete androgens, which will be used by the granulosa cells (part of the theca cells) to produce estradiol which will support the FSH induced follicular development.
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