Biology: At the Replication Fork: Lagging Strand

http://www.mindbites.com/lesson/4046 for full video

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[luckyspunk27]

DUUUUUUUDDDDEEEE!!!!!!! PUT UP YOUR WHOLE VIDEO!!!! I GOT A TEST IN A WEEK, I TOTALLY GET THE WAY YOU TEACH! YOUR A GOOD TEACHER. BUT I'M BROKE.....CANT BUY ALL YOUR VIDEOS, JUST NEED THE INFO.

[cecitacecita]

@luckyspunk27

Hello How was your test??? what kind of test it was??

[Diana5513]

@luckyspunk27 haha how did you do on your test?

[reimoj]

YOUR killing MEEEE! i have a test tomorrow, i need this video SOO bad just this one and im broke i cant buy this snif snif snif I NEEED YOUU!!

[Zolrak666]

@Medicalmarcl Yep, I get that, just to note that there is some uracil in there, obviously the fragment won't be DNA since uracil is never found in desoxiribose. By the way, I didn't know RNA primers were made in the leading strand.

[Medicalmarcl]

@Zolrak666

hmm..it si not just so:

1) The RNA primase make little burst of RNA even in the leading strand and not only in the lagging.

Just one In the leading strand and one for every Okazaki fragment in the lagging. 2)As you said, during the replication the RNA primase creates a little segment of RNA making a short double strand of hybrid DNA-RNA anyway the Uracile is contained in the RNA strand of the hybrid RNA-DNA and never in the DNA one. I don't know if I explained right what i meant...

[Zolrak666]

@Medicalmarcl Well, it does contain uracile during replication due to the action of the RNA primase, wich makes little bursts of RNA primers so the DNA polymerase can replicate in the lagging strand, wich is NOT EXPLAINED IN THE VIDEO BECAUSE IT'S CUT OFF.

[musicmaineac94]

@Medicalmarcl yeah your right, Im studying for my apbio exam and just realized that this morning, thanks!

[Medicalmarcl]

@musicmaineac94 i think you are mistaking, this happens in the formation of mRNA (transcription) and not during the replication; the DNA never contains uracile.