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Wyss Insitute: Low-cost gene synthesis

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Uploaded by on Dec 15, 2010

Long stretches of DNA are currently created in a costly and time-consuming manner by stitching together short strings of nucleic acids known as oligonucleotides. Where the bottleneck occurs -- and where the expense mounts -- is in the production of the smaller building blocks, called oligonucleotides. Recent technological advances, discussed here by Wyss researcher Sriram Kosuri, have made it possible to create hundreds of thousands of these oligonucleotides on a single DNA microchip, resulting in a low-cost, reliable gene-synthesis technology. Learn more at http://wyss.harvard.edu/viewpressrelease/49

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